Figure 2:

Various cell types and the effect of hypoxia on these cell types in the mammalian hippocampus. Hypoxia has different effects at different parts of the neurogenic cascade, and promotes apoptosis beyond the NSC stage. The morphology of each cell type under intermittent hypoxia has not been studied.Therefore, while varying levels of hypoxia may effect different areas of the cascade differently, the effects of intermittent hypoxia, with consequent ROS formation has not been elucidated. There could be differences in number, morphology, and function, all of which need to interrogated to properly understand how the mammalian hippocampus responds to intermittent hypoxia.