Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 May 6;13:628860. doi: 10.3389/fnagi.2021.628860

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Zeng, Qi, Guo, Zhu, Tang, Yong, Xie, Wu, Zhang and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Ameliorate effects of Ganodenic acid A by regulating sphingolipid metabolism in 3 × Tg-AD mice. (A) Experimental procedure in 3 × Tg-AD mice; (B) The AD biomarkers of p-Tau, Aβ, APOE, TREM2, CD33, the inflammatory cytokines of TNF-α and NF-κB p65 and the autophagy level of LC3A/B were measured in brain tissues; (C) KEGG analysis of serum metabolites; (D) KEGG analysis of brain metabolites. Data are presented as the means ± SD of more than six independent experiments and six independent experiments in Western blot. *p < 0.05, **p < 0.01, and ***p < 0.001.