Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 May 19;13:16. doi: 10.1038/s41368-021-00123-7

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 5 — Overexpression of PPARγ partially rescued the altered signalling molecule expression and weakened ALP staining and ALP activity in Per2-knockdown ALC cells. a PPARγ was overexpressed in ALC-Per2-sh cells transfected with plasmids. With the increase in PPARγ expression, PER2 expression remained unchanged, while AKT1 and β-catenin phosphorylation levels were enhanced in the ALC-Per2-sh-pEnCMV-Pparγ group. b ALP staining and ALP activity were enhanced in ALC-Per2-sh-pEnCMV-Pparγ cells compared to those in ALC-Per2-sh-pEnCMV cells but still weakened compared to those in ALC-Con-pEnCMV cells. *P < 0.05; **P < 0.01; ***P < 0.001