Fig. 3.

The histomorphology of case 1-SMARCB1/INI1 deficient sinonasal carcinoma showing a diffuse infiltrative nests and cords (Hematoxylin and Eosin, 100 ×), b small cell carcinoma like pattern (Hematoxylin and Eosin, 200 ×), c intimate admixture of two population of cells; cells with moderate amount of cytoplasm, round vesicular nucleus and prominent nucleoli and basaloid cells (Hematoxylin and Eosin, 400 ×), d, e infiltration of islands of tumor cells in bone, there is marked fibroblastic proliferation and new bone formation giving rise to a fibrous dysplasia like reaction, (Hematoxylin & Eosin, 100x), f Complete loss of INI1 protein in the tumor cells with positive internal control (immunostain, 400 ×)