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. 2020 Nov 3;15(2):555–565. doi: 10.1007/s12105-020-01246-9

Table 1.

Clinicopathological features of the SNUC cases

Case No. Age
(years)
Sex Signs and symptoms Imaging findings Histomorphological features Treatment &
follow up
1 40 F Right sided nasal mass Nasal mass with intracranial extension Papillary pattern, perivascular arrangement, basaloid morphology, necrosis NA
2 38 M Swelling below left orbit Mass in the maxillary sinus with extension into inferior orbital wall and infra-temporal fossa Sheets of large cells with moderate cytoplasm, vesicular nucleus & conspicuous nucleoli NA
3 17 M Nasal mass with left cervical LN CECT face and neck-large heterogeneously enhancing infiltrative soft tissue lesion centred in left nasopharynx, pterygo-maxillary space, left hemisphenoid, parasellar, paraclival region & left maxillary antrum Diffuse infiltrative pattern, Trabecular and cords of tumor cells, small cell carcinoma like pattern

No surgery, treated with chemo & radiotherapy

DOD, 3 months after the biopsy diagnosis

4 27 M Right sided nasal mass of 2-year duration CECT–small polypoidal enhancing lesion extending from anterior aspect of inferior turbinate with contiguous extension to lateral nasal wall Diffuse and nest like patterns, sarcomatoid areas, focal rhabdoid morphology WLE of the mass. Alive without any recurrence (2 years duration)
5 33 M Right sided polypoidal nasal mass NA Single cells, small nest, sheets of tumor cells variable amount of cytoplasm, round vesicular nucleus and prominent nucleoli, lymphoma like morphology NA
6 50 M Left nasal obstruction, bleeds on touch NA Nest of large tumor cells with moderate amount of cytoplasm, round nuclei & conspicuous nucleoli Treatment details were not available. DOD, 1 year after the diagnosis

SNUC sinonasal undifferentiated carcinoma, SDSC SMARCB1/INI1 deficient sinonasal carcinoma, NA not available, DOD died of diseases, WLE wide local excision