Table 1.
Clinical, demographic and pathological data of the patients in this study
| Sr. no | Age (yr) | Sex | Ca level (mg/dL) | PTH (ng/L) | Symptoms | Max. size | FS | Pattern | Nuclear atypia and nucleoli | Fibrous band |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 67 | M | 12.35 | 850 | Case of PA; muscle pain, anorexia | 1.8 | Favor PC | Nodular | Absent | + |
| 2 | 46 | F | 15.63 | 1098 | Right jaw swelling | 2.5 | Favor PC | Nodular | Moderate atypia, macronucleoli | + |
| 3 | 50 | M | 11.9 | 1389 | Backache, joint pain, left neck swelling | 3 | Favor PA | Nodular | Absent | + |
| 4 | 23 | F | 13.33 | 910 | Right shoulder pain | 3 | PC | Solid | Absent | − |
| 5 | 51 | F | NA | NA | NA | NA | ND | Nodular | Absent | + |
| 6 | 41 | F | 8.5 | 82 | Right neck swelling | 3.5 | Favor PC | Nodular | Nucleoli | + |
| 7 | 73 | F | 11.8 | 263 | Incidental d/t raise Ca | 2.5 | Favor PC | Nodular | Absent | + |
| 8 | 62 | M | 15.9 | 1150 | Right humerus fracture | 2 | ND | Nodular | Moderate atypia, macronucleoli | + |
| 9 | 32 | M | 15.8 | 1861 | Shoulder & back pain | 3.5 | ND | Solid | Moderate atypia | − |
| 10 | 25 | M | 17.8 | 1072 | Abdominal pain & vomiting | 3.5 | Favor PC | Nodular | Absent | + |
| 11 | 61 | F | 12.2 | 365 | Joint pain, lethargy, renal stones | 0.8 | Favor PC | Nodular | Moderate atypia | + |
| 12 | 53 | M | 13.9 | 363 | Incidental d/t raise Ca | 1.9 | ND | Nodular | Absent | + |
| 13 | 49 | M | 12.1 | 971 | Multiple lytic lesion | 1.4 | Favor PC | Solid | Moderate atypia | − |
| 14 | 48 | F | NA | NA | NA | NA | ND | Nodular | Absent | + |
| 15 | 53 | F | 14.4 | NA | Right flank pain, renal stone | NA | NA | Solid | Marked atypia | − |
| 16 | 42 | F | NA | NA | NA | NA | NA | Nodular | Absent | + |
| 17 | 55 | F | NA | NA | NA | NA | NA | Nodular | Absent | + |
| 18 | 21 | M | NA | NA | NA | NA | NA | Solid | Moderate atypia, nucleoli | − |
| 19 | 42 | M | NA | NA | NA | 1.5 | ND | Solid | Absent | − |
| 20 | 63 | M | NA | NA | NA | 2.4 | NA | Nodular | Moderate atypia | + |
| Sr. no | Mitosis (/10HPF) | Necrosis | Cap. inv | Vas. Inv | ST invasion | Gland involved | Adj treatment | Follow-up (months) | Outcome | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Absent | − | + | + | − | Right inf | Adj RT | 09 | Alive | |
| 2 | < 1 | − | + | + | + | Left Ectopic (upper med) | No RT | 41 | Alive | |
| 3 | < 1 | − | + | + | − | Left inf PC | No RT | 58 | Alive | |
| 4 | < 1 | − | + | + | − | Left inf | No RT | 36 | Alive | |
| 5 | < 1 | − | + | + | + | Left | No RT | 25 | Alive | |
| 6 | 1–2 | + large | + | + | − | Right inf | Adj RT, later Pall RT | 06 | DOD | |
| 7 | 3–4 | − | + | + | + | Right inf | Adj RT | 19 | Alive | |
| 8 | < 1 | − | + | + | + | Right inf | Adj RT | 44 | DOD | |
| 9 | 1–2 | − | + | + | − | Right inf | No RT | 12 | Alive | |
| 10 | < 1 | + focal | + | + | + | Right inf | Adj RT | 24 | Alive | |
| 11 | Absent | − | + | + | − | Right sup | Adj RT | 12 | Alive | |
| 12 | Absent | − | + | + | + | Left inf | Adj RT | 10 | Alive | |
| 13 | < 1 | − | + | + | + | Right inf | No RT | 09 | Alive | |
| 14 | < 1 | − | + | − | − | Right | No RT | 40 | Alive | |
| 15 | < 1 | − | + | + | + | Right inf | No RT | 10 | Alive | |
| 16 | < 1 | − | + | + | + | NA | NA | NA | NA | |
| 17 | < 1 | − | + | + | + | Left inf | Pall RT | 16 | Alive | |
| 18 | < 1 | + focal | + | + | − | NA | NA | NA | NA | |
| 19 | < 1 | − | + | + | − | NA | NA | NA | NA | |
| 20 | 1–2 | + focal | + | + | − | NA | NA | NA | NA | |
Adj, adjuvant; Ca, calcium; Cap, capsular; DOD, dead of disease; d/t, due to; FS, frozen section; Inf, inferior; Max, maximum; Med, mediastinal; NA, not available; ND, not done; PA, parathyroid adenoma; Pall, palliative; PC, parathyroid carcinoma; PTH, paratharmone; RT, radiotherapy; ST, soft tissue; sup, superior; Vas, vascular; Yr, years; +, present; −, absent; /10HPF, per 10 high power fields