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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: J Intensive Care Med. 2020 Nov 20;37(1):83–91. doi: 10.1177/0885066620973917

Table 2.

Regression analyses evaluating impact of not receiving 30 mL/kg by three hours

Mortality Delayed Hypotension ICU Admit ICU LOS Intubation
ABW IBW ABW IBW ABW IBW ABW IBW ABW IBW
OR (95% CI) OR (95% CI) OR (95% CI) β (95% CI) OR (95% CI)
Failed 30by3 1.78 (1.18–2.69) 1.28 (0.87–1.91) 0.94 (0.69–1.29) 1.00 (0.74–1.35) 0.76 (0.55–1.05) 0.73 (0.54–0.99) 2.40 (0.84–3.95) 1.58 (0.07–3.08) 1.26 (0.79–1.99) 0.87 (0.56–1.36)
MEDS 1.16 (1.12–1.21) 1.16 (1.12–1.21) 1.13 (1.09–1.17) 1.13 (1.09–1.17) 1.12 (1.08–1.16) 1.12 (1.08–1.16) 0.22 (0.06–0.38) 0.22 (0.07–0.38) 1.05 (1.00–1.10) 1.05 (1.00–1.09)
Time to Abx 1.02 (0.97–1.07) 1.02 (0.97–1.07) 1.02 (0.98–1.07) 1.02 (0.98–1.07) 1.00 (0.96–1.05) 1.01 (0.96–1.05) 0.02 (−0.24–0.27) 0.05 (−0.20–0.30) 1.00 (0.95–1.06) 1.01 (0.96–1.07)
Lactate 1.18 (1.12–1.25) 1.17 (1.11–1.24) 0.99 (0.94–1.04) 0.99 (0.94–1.04) 1.40 (1.28–1.54) 1.40 (1.28–1.53) 0.19 (−0.02–0.40) 0.18 (−0.03–0.39) 1.27 (1.19–1.36) 1.26 (1.18–1.35)
Age 1.00 (0.99–1.02) 1.01 (0.99–1.02) 0.99 (0.98–1.00) 0.99 (0.98–1.00) 0.99 (0.98–1.00) 0.99 (0.98–1.00) −0.03 (−0.07–0.02) −0.03 (−0.07–0.02) 0.99 (0.98–1.00) 0.99 (0.98–1.00)
Male sex 0.60 (0.41–0.86) 0.60 (0.41–0.86) 0.76 (0.58–1.00) 0.76 (0.57–1.00) 0.89 (0.67–1.18) 0.92 (0.70–1.23) −0.76 (−2.09–0.57) −0.78 (−2.13–0.57) 1.06 (0.71–1.58) 1.11 (0.74–1.67)
UW 1.11 (0.61–2.02) 1.01 (0.56–1.81) 0.72 (0.45–1.14) 0.72 (0.46–1.15) 0.63 (0.39–1.02) 0.67 (0.41–1.08) 1.41 (−0.90–3.73) 1.00 (−1.33–3.32) 0.62 (0.27–1.41) 0.60 (0.26–1.36)
OW 0.83 (0.52–1.33) 0.93 (0.59–1.48) 1.07 (0.75–1.52) 1.05 (0.74–1.50) 0.78 (0.54–1.12) 0.73 (0.51–1.05) 0.36 (−1.37–2.09) 0.76 (−0.95–2.47) 1.12 (0.66–1.90) 1.17 (0.70–1.98)
Obese 0.74 (0.45–1.20) 0.89 (0.56–1.41) 1.04 (0.73–1.50) 1.02 (0.72–1.44) 1.01 (0.70–1.47) 0.94 (0.66–1.33) −0.02 (−1.78–1.73) 0.75 (−0.92–2.41) 1.51 (0.90–2.55) 1.68 (1.03–2.74)
ESRD 1.30 (0.72–2.35) 1.40 (0.77–2.55) 1.72 (1.03–2.87) 1.69 (1.01–2.83) 1.45 (0.89–2.35) 1.49 (0.92–2.43) 0.67 (−1.53–2.87) 0.81 (−1.42–3.03) 0.76 (0.37–1.59) 0.86 (0.41–1.81)
HF 1.33 (0.89–1.99) 1.40 (0.94–2.11) 1.71 (1.21–2.43) 1.69 (1.19–2.40) 2.03 (1.43–2.88) 2.08 (1.46–2.97) 0.38 (−1.17–1.93) 0.55 (−1.02–2.11) 1.00 (0.61–1.62) 1.07 (0.66–1.76)

Table 2. Multivariate regression analyses for mortality, delayed hypotension, ICU admission, ICU LOS, and intubation. The table shows the impact of not receiving 30 mL/kg compared to receiving 30 mL/kg among of other controller variables listed. Reference group for BMI categories is normal weight.