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. 2021 May 9;24(1):503. doi: 10.3892/mmr.2021.12142

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Copyright: © Zhou et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 7. — lncRNA NEAT1 downregulates the expression levels of endoplasmic reticulum stress-related proteins. Expression levels of endoplasmic reticulum stress-, (A and B) apoptosis- and autophagy-related proteins were detected via western blotting. (C) lncRNA NEAT1 and miR-500a expression levels were determined via reverse transcription-quantitative PCR. *P<0.05, **P<0.01 and ***P<0.001 vs. vector; ^###P<0.001 vs. OverExp-NEAT1 + mimic NC. lncRNA, long non-coding RNA; NEAT1, nuclear paraspeckle assembly transcript 1; OverExp, overexpression; miR, microRNA; NC, negative control; GRP78, 78-kDa glucose-regulated protein; XBP-1, X-box binding protein-1; CHOP, C/EBP homologous protein; Atg5, autophagy-related gene 5.