Table 2.
Atrial fibrillation burden, episode duration and frequency as continuous variables associated with health-related quality of life in adjusted and unadjusted models.
| Simple regression analyses (141 patients) |
Multiple regression analysesa (114 patients) |
|||||||
|---|---|---|---|---|---|---|---|---|
| General health |
Vitality |
General health |
Vitality |
|||||
| Estimate (95% CI) | P-value | Estimate (95% CI) | P-value | Estimate (95% CI) | P-value | Estimate (95% CI) | P-value | |
| AF burden, %b | −0.65 (−1.54–0.26) |
0.16 | −1.58 (−2.60 to −0.55) |
0.003 | −1.00 (−2.19–0.18) |
0.10 | −1.34 (−2.67 to −0.02) |
0.047 |
| AF episode duration, minutesc | −0.04 (−0.17–0.09) |
0.57 | −0.20 (−0.35 to −0.04) |
0.013 | −0.03 (−0.20–0.14) |
0.73 | −0.13 (−0.32–0.07) |
0.21 |
| AF frequency, episodes per month | 0.01 (−0.02–0.04) |
0.34 | 0.02 (−0.02–0.05) |
0.35 | 0.02 (−0.02–0.05) |
0.45 | 0.01 (−0.03–0.05) |
0.63 |
AF = Atrial fibrillation; AF burden = % of time spent in AF; AF episode duration = AF episode duration in minutes; AF frequency = AF episodes/month; CI = Confidence interval; General health and Vitality = dimensions in the 36–Item Short Form Health Survey (SF-36).
a
Models adjusted for sex, heart rate > 110 beats per minute during AF, hypertension, type of AF and ongoing beta-blocker medication.
b
With 10% increase.
c
With 1-hour increase and 122 patients included in simple regression analyses and 106 patients in multiple regression.