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. 2021 May 6;15:100335. doi: 10.1016/j.ynstr.2021.100335

Table 2.

Summary of results indicating distinct Susceptible phenotypes. Results were observed in both males and females unless otherwise indicated.

Task Effects of Susceptibility
Pre-stress
 Continuous access 2-bottle choice No effect
 Light-dark transition test Reduced entries and time spent in light compartment (females only)
Fear measures
 Generalization test Increased fear generalization
 SEFL test Increased fear conditioning
 Extinction Impaired fear extinction
 Aversive acoustic stimulus Increased fear conditioning



Anxiety measures
 Open field test Reduced mobility, blunted response to light onset (males only)
 Elevated plus maze No effect
 Light-dark transition test Reduced entries into light compartment
Alcohol measures
 Intermittent access 2-bottle choice Increased alcohol consumption and preference (males only)