Table 2. Effect Size of Progression Patterns With Regard to Development of HGD or HGD/Invasive Cancer.
| Pattern | HGD | HGD/invasive cancer | ||
|---|---|---|---|---|
| OR (95% CI) | P value | OR (95% CI) | P value | |
| No WF/HRS (null) | 1 [Reference] | NA | 1 [Reference] | NA |
| Stable WF | 2.48 (0.64-9.57) | .19 | 0.95 (0.36-2.50) | .92 |
| New WF | 1.06 (0.44-2.54) | .90 | 1.14 (0.60-2.17) | .69 |
| Additional WF | 3.24 (1.38-7.60) | .007 | 2.36 (1.14-4.88) | .02 |
| Stable HRS | 2.79 (0.90-8.66) | .08 | 2.11 (0.76-5.90) | .15 |
| From null to HRS | 1.38 (0.45-4.24) | .58 | 2.32 (0.99-5.42) | .05 |
| From WF to HRS | 2.87 (1.01-8.18) | .048 | 2.57 (1.02-6.50) | .046 |
Abbreviations: HGD, high-grade dysplasia; HRS, high-risk stigmata; NA, not applicable; OR, odds ratio; WF, worrisome feature.