FIGURE 2.

Cultured lymphocyte energy sensing pathway protein expression. Lymphocytes were lysed and assayed for protein expression as described in materials and methods. (a) Lymphocyte PINK/ACTIN densitometry by APOE genotype. (b) Lymphocyte pSIRT1/SIRT1 densitometry by APOE genotype. (c) Lymphocyte pMTOR/MTOR densitometry by APOE genotype. (d) Lymphocyte AceCS1/ACTIN densitometry by APOE genotype. (e) Lymphocyte ATP CL/ACTIN densitometry by APOE genotype. (f) Lymphocyte ACC densitometry by APOE genotype. (g) ACC densitometry in autopsied human brain samples by APOE genotype or diagnosis. Red indicates ND subjects when data are separated by APOE genotype. Green indicates APOE ε4 Non‐Carriers when data are separated by diagnosis. * indicates p < 0.05, ** indicates p < 0.01. Data are shown as mean ± SEM