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. Author manuscript; available in PMC: 2021 Sep 1.
Published in final edited form as: Clin Pharmacol Ther. 2020 May 23;108(3):671–680. doi: 10.1002/cpt.1847

Table 1.

Expression of drug transporters relevant for paclitaxel disposition in SH-SY5Y-derived neurons and human dorsal root ganglion.

Transporter gene qPCR Expression relative to SH-SY5Y ABCB1 LC-MS/MS fmol/μg protein
SH-SY5Y-derived neurons Human dorsal root ganglion SH-SY5Y-derived neurons Human dorsal root ganglion
ABCB1 1.0 0.04 3.1 0.06
ABCC1 0.2 0.06 Below LoQ 0.05
ABCC2 0.002 Not detected Below LoQ Below LoQ
ABCG2 Not detected 0.04 Not measured Not measured
SLCO1B1 Not detected Not detected Not measured Not measured
SLCO1B3 Not detected 0.006 Not measured Not measured