RPLP1 is highly expressed in HCC tissues and cells, and overexpression of RPLP1 is associated with the prognosis of patients with HCC. (A) High RPLP1 expression in HCC tissue is associated with a poor OS rate. (B) OS analysis was performed using the log-rank, according to follow-up information of patients with HCC. (C) RPLP1 expression was associated with tumor grade of HCC. (D) Reverse transcription-quantitative PCR analysis was performed to detect RPLP1 mRNA expression in the human liver cell line and the HCC cell lines. *P<0.05, **P<0.01 and ***P<0.001 vs. respective control. RPLP1, ribosomal protein LP1; HCC, hepatocellular carcinoma; OS, overall survival; TPM, transcripts per million; TCGA, The Cancer Genome Atlas; LIHC, liver hepatocellular carcinoma.