Table 1.
Baseline characteristics of postmenopausal patients with major depressive disorder
| Characteristics | Venlafaxine (n = 82) |
Fluoxetine (n = 90) |
P |
|---|---|---|---|
| Age (years), mean ± SD | 56.7 ± 6.8 | 56.9 ± 5.8 | 0.83 |
| BMI (kg/m2), mean ± SD | 23.9 ± 3.8 | 23.0 ± 2.9 | 0.14 |
| Age at onset (years), mean ± SD | 52.3 ± 7.9 | 51.5 ± 8.2 | 0.55 |
| Duration of illness (years), mean ± SD | 5.7 ± 6.2 | 6.3 ± 6.9 | 0.54 |
| Previous episodes, mean ± SD | 2.0 ± 1.9 | 2.0 ± 2.3 | 0.88 |
| HAMD-24 total score, mean ± SD | 30.5 ± 7.3 | 31.7 ± 8.5 | 0.34 |
| Anxiety/somatization score, mean ± SD | 8.3 ± 2.6 | 8.8 ± 2.5 | 0.22 |
| CGI-I score, mean ± SD | 3.7 ± 1.2 | 3.7 ± 1.0 | 0.78 |
| Family history, n (%) | 10 (12.2) | 9 (10.0) | 0.65 |
BMI body mass index, CGI-I Clinical Global Impression of Improvement, HAMD-24 24-item Hamilton Depression Rating Scale, SD standard deviation