Table 2.
The mixed effect model analysis results of the two groups of HAMD-24,anxiety/somatization factor score
| Group | Time | Research center | Research center*Group | Time*group | |
|---|---|---|---|---|---|
| HAMD(8w, FAS) | |||||
| F | 12.0 | 68.8 | 3.04 | 0.01 | 0.17 |
| P | 0.001 | < 0.01 | 0.08 | 0.92 | 0.95 |
| HAMD(8w, PP) | |||||
| F | 8.7 | 64.1 | 3.2 | 0.05 | 0.03 |
| P | 0.004 | < 0.01 | 0.08 | 0.82 | 0.98 |
| Anxiety/somatization factor(8w, FAS) | |||||
| F | 14.5 | 58.4 | 0.67 | 0.97 | 0.9 |
| P | < 0.01 | < 0.01 | 0.42 | 0.33 | 0.47 |
Data were analyzed using a mixed-effect model for repeated measures (MMRM). HAMD-24 24-item Hamilton Depression Rating Scale, FAS full analysis set, PP per-protocol analysis, * interaction