Table 7.

Multivariable analysis of factors associated with multiple relapses in GCA patients.

Variables	Univariate HR [95% CI]	p	Multivariate HR [95% CI]	p
Negative TAB	1.78 [0.99–3.21]	0.05	2.29 [1.18–4.45]	0.015*
Scalp tenderness	1.79 [0.94–3.42]	0.08	1.76 [0.84–3.67]	0.13
Polymylagia rheumatica	2.61 [1.41–4.84]	0.002	1.86 [0.79–4.38]	0.16
Peripheral musculoskeletal manifestation	3.28 [1.80–5.99]	0.0001	2.78 [1.23–6.28]	0.014*
Upper limb ischemia	4.08 [1.25–13.30]	0.02	8.84 [2.48–31.56]	0.001*
Aortitis of ascending thoracic aorta	0.48 [0.23–1.00]	0.05	0.41 [0.15–1.12]	0.08
Aortitis descending thoracic aorta	0.53 [0.28–1.02]	0.06	0.58 [0.24–1.44]	0.24
Inflammation of arm arteries	1.58 [0.82–3.04]	0.17	2.39 [1.02–5.58]	0.04*

^*Significant at p < 0.05.

CI, confidence interval; GCA, giant cell arteritis; HR, hazard ratio; TAB, temporal artery biopsy.