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. 2021 Mar 19;40(3):226–241. doi: 10.1177/1091581821998945

Figure 2.

Figure 2.

SRK-181 has no effect on human platelet aggregation, activation, and binding. (A) Platelet aggregation with ADP agonist was not altered by SRK-181 as compared to vehicle control. (B) Platelet activation with ADP agonist was not affected by increasing concentration of SRK-181, compared with the vehicle control. (C) SRK-181 binding to unactivated or activated platelets was low and did not increase with higher concentrations, as compared to vehicle control. Data shown in panel (A) are the mean of 4 donors ± standard deviation, while data shown in panels (B) and (C) are replicate means from one donor ± standard deviation and are representative of 4 donors.