Table 2.

Persistent Cases

Patient	Case	Publication (Year)	Age	Sex	Underlying Conditions	Immunosuppressants	Antiviral Treatment	Infection Length, Days	Fatal?
Pe1	Choi et al [8]	New Engl J Med (2020)	45	M	Antiphospholipid antibody syndrome	Rituximab, eculizumab, cyclophosphamide, corticosteroids	Remdesivir, casirivimab and imdevimab	154	Yes
Pe2	Baang et al [10]	J Infect Dis (2021)	60	M	Refractory mantle cell lymphoma	CD20 bispecific Ab, B-cell directed Ab, cyclophosphamide, doxorubicin, prednisone	Remdesivir, convalescent plasma	156	Yes
Pe3	Avanzato et al [9]	Cell (2020)	71	F	CLL, acquired hypogammaglobulinemia	…	Convalescent plasma	156	No
Pe4	Kemp et al [11]	Nature (2021)	…	…	Marginal B-cell lymphoma, hypogammaglobulinemia	B-cell–depleting therapy	Remdesivir, convalescent plasma	102	Yes
Pe5	Tarhini et al [27]	J Infect Dis (2021)	66	M	HIV, multifocal leukoencephalopathy from JC virus	…	…	124	No
Pe6–1	TTruong et al [28]	EBioMedicine (2021)	<5	F	B-cell ALL	Dexamethasone, vincristine, peg- asparaginase, methotrexate, 6-MP, doxorubicin	…	91	No
Pe6–2			20–25	M	B-cell ALL	CD-19–directed CAR-T cell therapy (tisagenlecleucel), cylcophosphamide, fludarabine	Remdesivir, convalescent plasma	250+	No
Pe6–3			<5	M	B-cell ALL	Cyclophosphamide, cytarabine, thioguanine, vincristine, dexamethasone, methotrexate, mercaptopurine	…	196	No
Pe7	Borges et al [29]	Virological	61	F	Diffuse large B-cell lymphoma	Chemotherapy (unspecified), methotrexate, corticosteroids	Remdesivir	197	No

Abbreviations: Ab, antibody; ALL, acute lymphoblastic leukemia; CAR, chimeric antigen receptor; CLL, chronic lymphocytic leukemia; F, female; HIV, human immunodeficiency virus; JC virus, John Cunningham virus; J Infect Dis, Journal of Infectious Diseases; M, male; New Engl J Med, New England Journal of Medicine.