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. 2021 Apr 27:bbab118. doi: 10.1093/bib/bbab118

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© The Author(s) 2021. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com

This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.

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Female patients have higher antiviral activity of ZNF protein than male patients. (A) UMAP cluster diagram shows the single-cell distribution of COVID-19 patients of different genders. (B) Stacked histogram shows the cell ratio of COVID-19 patients of different genders. (C and D) Box diagram showing the antiviral activity of ZNF protein in mild and severe COVID-19 patients. (E) The box diagram shows the antiviral activity of ZNF protein in each cell cluster in mild COVID-19 patients. (F) The box diagram shows the antiviral activity of ZNF protein in each cell cluster in severe COVID-19 patients. Kruskal–Wallis test was used for statistical significance. Kruskal–Wallis test was used for statistical significance, ^*^*^*P < 0.001, ^*^*P < 0.01, ^*P < 0.05, ^nsP > 0.05.