Table 4.

Heart failure decompensation details

	CareLine alert	Device Alert	Action
			Home	Hospital
Before LD
Patient 1	Weight gain >2 kg/5days	NA	IV diuretics
Patient 2 PM VR BS	Weight gain >4 kg/Ref Δ Blood urea >20%	No	↑ oral diuretics	Hospitalization 7 days after
Patient 3	Weight gain >4 kg/Ref Weight gain >2 kg/5days Δ Symptoms HR > 100 b.p.m./3 days	NA		Hospitalization
Patient 4 CRT-D Bio	Weight gain >4 kg/Ref Weight gain >2 kg/5days Δ Symptoms Δ NT-proBNP >20%	No	↑ oral diuretics	Hospitalization 7 days after
Patient 5 ICD DR Med	No	TriageHF™ index high for 9 days		Hospitalization
Patient 1	Weight gain >2 kg/5days	NA	IV diuretics	Hospitalization
Patient 6 PM VR MP	Weight gain >4 kg/Ref Weight gain >2 kg/5days Δ Symptoms	NA	↑ oral diuretics	Hospitalization 3 days after
During LD
Patient 7 ICD DR Med	Weight gain >4 kg/Ref Weight gain >2 kg/5days	No	↑ oral diuretics
Patient 8 CRT-D Ab	Weight gain >2 kg/5days Δ Symptoms	↑AT/AF burden ↓%BIV pacing	↑ oral diuretics ↑ Sab-Valsartan
Patient 4 CRT-D Bio	Weight gain >4 kg/Ref Δ Symptoms	No	↑ oral diuretics
Patient 1	Weight gain >2 kg/5days	NA	IV diuretics
Patient 9 CRT-P Ab	No	No		Hospitalization
Patient 1	Weight gain >2 kg/5days	NA	IV diuretics

Overview of the nine patients with heart failure decompensations under remote monitoring presented in chronological order. The first column indicates the patient’s number and the device model. PM VR BS, pacemaker VR Boston Scientific; CRTD bio, CRT-Defibrillator Biotronik; ICD DR Med, ICD DR Medtronic; CRT-D Ab, CRT-Defibrillator Abbott; CRT-P Ab, CRT-Pacemaker Abbott. The second column depicts the CareLine Solutions alerts at the time of HF decompensation diagnosis. Weight gain >4 kg/Ref: weight gain in comparison to the weight patient’s reference. Weight gain >2 kg/5days: gain of more than 2 kg in five consecutive days. Δ Symptoms: worsening of symptoms based on the questionnaire. HR > 100 b.p.m./3 days: mean heart rate above 100 b.p.m. on three consecutive days. Δ Blood urea >20% and Δ NT-proBNP >20%: increase >20% of the last known value. The third column depicts the CIEDs remote monitoring alerts at the time of HF decompensation diagnosis. The last columns indicate the medical interventions required.