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. Author manuscript; available in PMC: 2021 May 20.
Published in final edited form as: Infect Genet Evol. 2018 Nov 19;67:191–209. doi: 10.1016/j.meegid.2018.11.009

Table 1.

Summary of vector competence estimates across Ae. aegypti geographic populations to 1) DENVs, 2) ZIKV, 3) YFV; 4) CHIKV; 5) dual-infections and 6) infections with arboviruses other than DENVs, YFV, ZIKV and CHIKV.

Vector Competence
Reference Mosquito origin Virus genotype and strain Infection Route, virus
dose1 		Results7
1) DENVs
Calvez et al., 2018 Noumea, NC DENV-1 NC14-17022014-806 BM2, 106 IR in bodies 50 at 7 dpi, 10 at 14 dpi, 8 at 21 dpi; IR in the heads 60 at 7 dpi, 100 at 14 dpi, 100 at 21 dpi; TR 3 at 7dpi, 3 at 14 dpi, 8 at 21 dpi
Ouvea, NC DENV-1 NC14-17022014-806 BM, 106 IR in bodies 53 at 7 dpi, 53 at 14 dpi, 33 at 21 dpi; IR in the heads 100 at 7 dpi, 87 at 14 dpi, 90 at 21 dpi; TR 3 at 7dpi, 13 at 14 dpi, 13 at 21 dpi
Poindimie, NC DENV-1 NC14-17022014-806 BM, 106 IR in bodies 33 at 7 dpi, 13 at 14 dpi, 17 at 21 dpi; IR in the heads 70 at 7 dpi, 100 at 14 dpi, 80 at 21 dpi; TR 0 at 7dpi, 3 at 14 dpi, 0 at 21 dpi
Papeete, Thaiti Island DENV-1 NC14-17022014-806 BM, 106 IR in bodies 47 at 21 dpi; IR in the heads 100 at 21 dpi; TR 3 at 7dpi, 35 at 21 dpi
Serrato et al., 2017 Valle Grande, Col DENV-2 NG BM, 108.1–107 IR 68 at 15 dpi
Paso del Comercio, Col DENV-2 NG BM, 108.1–107 IR 55 at 15 dpi
Siloe, Col DENV-2 NG BM, 108.1–107 IR 52 at 15 dpi
Mariano Ramos DENV-2 NG BM, 108.1–107 IR 52 at 15 dpi
Hanoi, Viet8 DENV-2 strain 6H, Hanoi Viet BM, 2.8×107 IR 4.2 at 25°C; 9.1 at 27°C; 80 at 32°C
DENV-2 strain 434S, Long An Province, Viet BM, 3.77×107 IR 8.1 at 25°C; 13 at 27°C; 4.2 at 32°C
Ho Chi Minh City, Viet DENV-2 strain 6H, Hanoi Viet BM, 2.8×107 IR 10.8 at 25°C; 2.8 at 27°C; 0 at 32°C
DENV-2 strain 434S, Long An Province, Viet BM, 3.77×107 IR 24.6 at 25°C; 9.8 at 27°C; 7.7 at 32°C
Vazeille et al., 20169 Center Cayenne, FG DENV-1 isol. from a 2009 patient living in Cayenne BM, 105–106 IR 20 at 8 dpi, 〰35 at 10 dpi, 〰50 at 14 dpi; TR different from 0 only at 14 dpi, when it reached 〰10
Center Cayenne, FG DENV-4 isol. from a 2009 patient living in Cayenne BM, 105–106 IR 〰40 at 8 dpi, 〰60 at 10 dpi, 〰60 at 14 dpi; TR different from 0 only at 14 dpi, when it reached 〰8
Scattered housing area, Cayenne, FG DENV-1 isol. from a 2009 patient living in Cayenne BM, 105–106 IR 〰20 at 8 dpi, 〰50 at 10 dpi, 〰78 at 14 dpi; TR was always 0
Scattered housing area, Cayenne, FG DENV-4 isol. from a 2009 patient living in Cayenne BM, 105–106 IR 〰40 at 8 dpi, 〰35 at 10 dpi, 〰58 at 14 dpi; TR different from 0 only at 14dpi, when it reached 〰15
Guo et al., 2016 Haikou strain, originally from Hainan province DENV-2-FJ10 BM, 1.75×105 IR in midgut 0 up to 3 dpi; 5 from 5-7 dpi; 15 at 9 dpi, 25 at 15 dpi; IR in salivary glands 0 up to 5 dpi; 4 at 7 dpi, 15 at 9 dpi, 17 at 15 dpi
DENV-2-FJ11 BM, 2×105 IR in midgut 0 up to 3 dpi; 5 at 5 dpi, 10 at 7 dpi; 25 at 9 dpi, 35 at 15 dpi; IR in salivary glands 0 up to 5 dpi; 4 at 7 dpi, 10 at 9 dpi, 25 at 15 dpi
Fansiri et al., 2016 Bangkok, Thai 14 DENV-1 Thai isol. BM, 1.5×105 −8.5 106 IR 0 (B3 viral strain, experiment 2) - 100 (K15 and K4 viral strains experiment 1; B1, B76 and K25 viral strains experiment 2)
Kamphaeng Phet Province, Thai 14 DENV-1 Thai isol. BM, 1.5×105 −8.5 106 IR 0 (K1 viral strain, experiment 2) - 100 (K25 viral strain experiment 1, B76 viral strain experiment 2)
Fernandes da Moura et al., 2015 Santiago Island, Capo Verde DENV-1 42735/BR PE BM, 5×104– 2×105 IR 0 at 7 dpi, 74,9 at 14 dpi, 20 at 21 dpi in midguts; IR 24,3 at 7 dpi, 0 at 14 dpi, 67,5 at 21 dpi in whole body; TR 55 at 14 dpi
DENV-2 3808/BR-PE BM, 1,4×105– 2×105 IR 60 at 7 dpi, 80 at 14 dpi, 20 at 21 dpi in midguts; IR 0 at 7 dpi, 0 at 14 dpi, 92.5 at 21 dpi in whole body; TR 55 at 14 dpi
DENV-3 85469/BR-PE BM, 106 IR 12.5 at 7 dpi, 65 at 14 dpi, 75 at 21 dpi in midguts; IR 58,4 at 7dpi, 76,9 at 14 dpi, 93,8 at 21 dpi in whole body; TR 50 at 14 dpi
DENV-4 1385 (U1842) BM, 106 IR 0 at 7 dpi, 0 at 14 dpi, 9 at 21 dpi in midguts; IR 0 at 21 dpi in whole body; TR 0 at 14 dpi
Poole-Smith et al., 2015 Patillas, PR DENV-1 Hawaii BM, 5–6 Log10 IR 15, TR 3
DENV-2 NG C BM, 5–6 Log10 IR 17, TR 5
DENV-3 H87 BM, 5–6 Log10 IR 18, TR 2
DENV-4 H241 BM, 5–6 Log10 IR 62, TR 42
Dickson et al., 201410 Fatick, S DENV-2-75505 sylvatic genotype from S BM, 1.5×106 IR 61
Bignona, S DENV-2-75505 sylvatic genotype from S BM, 1.5×106 IR 29
Richard Toll, S BM, 1.5×106 IR 30
DENV-2-75505 sylvatic genotype from S
Goudiry, S DENV-2-75505 sylvatic genotype from S BM, 1.5×106 IR 39
Aedes aegypti formosus Kedougou, S, sylvatic DENV-2-75505 sylvatic genotype from S BM, 1.5×106 IR 60
Aedes aegypti formosus PK10, S, sylvatic DENV-2-75505 sylvatic genotype from S BM, 1.5×106 IR 57
Mont Rolland, S DENV-2-75505 sylvatic genotype from S BM, 107 IR 93
Rufisque, S DENV-2-75505 sylvatic genotype from S BM, 1.5×106 IR 33
Gaye et al., 2014 Sylvatic Aedes aegytpi formosus from Kedoungou, S DENV-1 IbH28328 BM3, 5×103.3 IR 40 at 7 dpi, 30 at 15 dpi, 50 at 20 dpi
Sylvatic Ae.aegytpi formosus from Kedoungou, S DENV3 H87 BM3, 5×103.3 IR 0 at 7 dpi, 8.3 at 15 dpi,
Domestic Ae.aegypti from Dakar, S DENV-1 IbH28328 BM3, 5×103.3 IR 0 at 7 dpi, 43.7 at 15 dpi, 30.8 at 20 dpi
Domestic Ae. aegypti from Dakar, S DENV3 H87 BM3, 5×103.3 IR 10 at 7 dpi, 15.2 at 15 dpi, 2.4 at 20 dpi
Alto et al., 2014 Key West, FL DENV-1/US/BID-V852/2006 BM, 6.8±0.5 log10 IR 10 at 7 dpi and 6 at 14 dpi in midguts; 10 at 7 dpi and 88 at 14 dpi in whole body
DENV-2/US/BID-V1041/2006 BM, 7.1±1.2 log10 IR 28 at 7 dpi, at 14 dpi, 28 at 21 dpi in midguts; IR 12 at 7 dpi, 27 at 14 dpi in whole body
Gonçalves et al., 20149 Belo Horizonte, BR DENV-2 from a hs of a patient from Belo Horizonte in 1991 BM, ntd IR 60 and TR 58 in 2009; IR 78 and TR 55 in 2011
Pongsiri et al., 2014 Phet Province, Thai six DENV-2 isol. from patients of the Phet Province in Thai BM, 3.5–6 log10 IR 20.9 at 7 dpi, 31.8 at 14 dpi
Ye et al., 20149 Cairns, Aus DENV-2 92-T strain isol. during a 1992 outbreak in Townsville BM, 106 IR 20-100 in midguts; 25-70 in heads
DENV-2 ET-300 strain isol. in Timor-Leste in 2000 BM, 106 IR 60-100 in midguts, 38-100 in heads
Rockhamton, Aus DENV-2 92-T strain isol. during a 1992 outbreak in Townsville BM, 106 IR 85-100 in midguts; 35-100 in heads
DENV-2 ET-300 strain isol. in Timor-Leste in 2000 BM, 106 IR 80-100 in midguts; 60-100 in heads
Chepkorir et al., 2014 Nairobi, Kenya DENV-2 from a hs (Sample N. 008/01/2012) BM, 105.08 mosquitoes kept at 26°C (Nairobi's average temperature) after infection, IR 12, disseminated infection 18
DENV-2 from a hs (Sample N. 008/01/2012) BM, 105.08 mosquitoes kept at 30°C (Kilifi's average temperature) after infection, IR 20, disseminated infection 8
Kifili, Kenya DENV-2 from a hs (Sample N. 008/01/2012) BM, 105.08 mosquitoes kept at 26°C (Nairobi's average temperature) after infection IR 5, disseminated infection 35
DENV-2 from a hs (Sample N. 008/01/ 2012) BM, 105.08 mosquitoes kept at 30°C (Kilifi's average temperature) after infection IR 10, disseminated infection 42
Guo et al., 2013 Haiku strain, Chi DENV-2 NG C BM4, 7.7 log10 IR in midguts at 1 dpi is 60; TR at 15 dpi 85.7
DENV-2 43 BM4, 7.2 log10 IR in midguts at 1 dpi is 48.5; TR at 15 dpi 56.3
Sim et al., 20139 Rockefeller strain DENV-2 NG C strain BM, 106–7 IR 7 dpi in midguts, 100
DENV4-WRAIR BM, 106–7 IR 7 dpi in midguts, 100
Orlano strain DENV-2 NG C strain BM, 106–7 IR 7 dpi in midguts, 0
DENV4-WRAIR BM, 106–7 IR 7 dpi in midguts, 0
Waco strain DENV-2 NG C strain BM, 106–7 IR 7 dpi in midguts, 15
DENV4-WRAIR BM, 106–7 IR 7 dpi in midguts, 10
PR, field DENV-2 NG C strain BM, 106–7 IR 7 dpi in midguts, 30
DENV4-WRAIR BM, 106–7 IR 7 dpi in midguts, 25
Saint Kitts, field DENV-2 NG C strain BM, 106–7 IR 7 dpi in midguts, 25
DENV4-WRAIR BM, 106–7 IR 7 dpi in midguts, 55
Por Fin, field DENV-2 NG C strain BM, 106–7 IR 7 dpi in midguts, 28
DENV4-WRAIR BM, 106–7 IR 7 dpi in midguts, 10
Puertp Triunfo, field DENV-2 NG C strain BM, 106–7 IR 7 dpi in midguts, 65
DENV4-WRAIR BM, 106–7 IR 7 dpi in midguts, 10
Singapore, field DENV-2 NG C strain BM, 106–7 IR 7 dpi in midguts, 90
DENV4-WRAIR BM, 106–7 IR 7 dpi in midguts, 10
Bangkok, field DENV-2 NG C strain BM, 106–7 IR 7 dpi in midguts, 10
DENV4-WRAIR BM, 106–7 IR 7 dpi in midguts, 10
Buckner et al., 2013 Key West, FL DENV-1 (strain BOLKW010) BM, 6.3±0.2 Log10 IR 93 in midguts, 80 in whole body
Carrington et al., 2013 Kamphaeng Phet Province, Thai DENV-1 BM1, 3,09–4.16×105 IR 28
Lourenço-De-Oliveira et al., 2013 Buenos Aires, Argentina DENV-2 Thai 1974 BM, 107 IR in whole bodies 66.7 at 14 dpi and 78.1 at 21 dpi; TR 10.5 at 14 dpi and 6.7 at 21 dpi
Corrientes, Argentina DENV-2 Thai 1974 BM, 107 IR in whole bodies 53.3 at 14 dpi and 76.7 at 21 dpi; TR 18.5 at 14 dpi and 36.4 at 21 dpi
Salto, Uruguay DENV-2 Thai 1974 BM, 107 IR in whole bodies 53.3 at 14 dpi and 76.7 at 21 dpi; TR 20 at 14 dpi and 17.9 at 21 dpi
Richards et al., 2012 Key West, FL DENV-1 isol. BOL-KW010 BM, 3.7 Log10 IR 89 in the abdomen, 100 in legs; TR 0 when mosquitoes were kept at 28°C
Key West, FL DENV-1 isol. BOL-KW010 BM, 3.7 Log10 IR 75 in the abdomen, 33 in legs; TR 0 when mosquitoes were kept at 30°C
Stock Island, FL DENV-1 isol. BOL-KW010 BM, 3.7 Log10 IR 75 in the abdomen, 100 in legs; TR 33 when mosquitoes were kept at 28°C
Stock Island, FL DENV-1 isol. BOL-KW010 BM, 3.7 Log10 IR 80 in the abdomen, 100 in legs; TR 0 when mosquitoes were kept at 30°C
Carvalho-Leandro et al., 20129 Petrolina, BR DENV-2 3808/BR-PE BM, 106–7 IR 25 at 3 dpi, 70 at 7 dpi, 77 at 15 dpi, 50 at 21 dpi in midguts; IR 10 at 3 dpi, 20 at 7 dpi, 58 at 15 dpi and 100 at 21 dpi in fat; TR 40 at 7 dpi, 10 at 15 dpi, 40 at 21 dpi
Recife, BR DENV-2 3808/BR-PE BM, 106–7 IR 5 at 3 dpi, 42,5 at 7 dpi, 20 at 15 dpi, 46.3 at 21 dpi in midguts; IR 0 at 3 dpi, 10 at 7 dpi, 70 at 15 dpi and 40 at 21 dpi in fat; TR 35 at 7 dpi, 60 at 15 dpi, 47.5 at 21 dpi
Rec-L Recife Lab. strain DENV-2 3808/BR-PE BM, 106–7 IR 5 at 3 dpi, 22 at 7 dpi, 20 at 15 dpi, 45 at 21 dpi in midguts; IR 0 at 3 dpi, 35 at 7 dpi, 35 at 15 dpi and 58 at 21 dpi in fat; TR 5 at 7 dpi, 20 at 15 dpi, 35 at 21 dpi
Sylla et al., 2009 D2MEB DENV-2 JAM1409 BM, 3.1×107–8 IR 51.2
D2S3 DENV-2 JAM1409 BM, 3.1×107–8 IR 92.3
Schneider et al., 2007 Bangkok, field DENV-2 JaM1409 BM, ntd IR 32.22 +/− 8.56
DS3 DENV-2 JaM1409 BM, ntd IR 45.95 +/− 17.76
Form, Flavivirus refractory strC2:C83ain from Nigeria DENV-2 JaM1409 BM, ntd IR 48.42 +/− 6.68
Ghana, field DENV-2 JaM1409 BM, ntd IR 27.44 +/− 6.03
Ibo 11, Dengue refractory strain from Nigeria DENV-2 JaM1409 BM, ntd IR 31.55 +/− 2.44
Mombasa, field DENV-2 JaM1409 BM, ntd IR 30.23 +/− 3.14
MOYO-R DENV-2 JaM1409 BM, ntd IR 19.54 +/− 9.73
MOYO-S, RED, mutant marker stock DENV-2 JaM1409 BM, ntd IR 53.60 +/− 14.16
DENV-2 JaM1409 BM, ntd IR 38.79 +/− 14.17
Trinidad, field DENV-2 JaM1409 BM, ntd IR 34.92 +/− 29.27
Diallo et al., 200811 Barkedji, S sylvatic DENV-2 AdR 140875 BM4, 1.6×107–106.5 IR 7.4
epidemic DENV-2 ArA 6894 BM4, 1.6×107–106.5 IR 1.74
Dakar, S sylvatic DENV-2 AdR 140875 BM4, 1.6×107–106.5 IR 7.8
epidemic DENV-2 ArA 6894 BM4, 1.6×107–106.5 IR 0
Ngoye, S sylvatic DENV-2 AdR 140875 BM4, 1.6×107–106.5 IR 17.2
epidemic DENV-2 ArA 6894 BM4, 1.6×107–106.5 IR 1.46
Ndougoubene, S sylvatic DENV-2 AdR 140875 BM4, 1.6×107–106.5 IR 9.3
epidemic DENV-2 ArA 6894 BM4, 1.6×107–106.5 IR 1.57
Kedougou, S sylvatic DENV-2 AdR 140875 BM4, 1.6×107–106.5 IR 1.35
epidemic DENV-2 ArA 6894 BM4, 1.6×107–106.5 IR 0
Koung Koung, S sylvatic DENV-2 AdR 140875 BM4, 1.6×107–106.5 IR 2.7
epidemic DENV-2 ArA 6894 BM4, 1.6×107–106.5 IR 1.85
Knox et al., 2003 Torres Strait, Aus DENV-2 92T BM5, 106.4 IR 96 at 8 dpi, 100 at 12 and 16 dpi; TR 0 at 8 dpi; 8 at 12 dpi, 76 at 16 dpi
DENV-4 97B BM5, 107 IR 80 at 8 and 12 dpi, 84 at 16 dpi, 72 at 20 dpi; TR 0 at 8 and 12 dpi, 16 at 16 dpi, 16 at 20 dpi
Charters Towers, Aus DENV-2 92T BM5, 106.4 IR 52 at 8 dpi, 60 at 8 dpi, 64 at 16 dpi; TR 8 at 8 dpi, 4 at 12 dpi, 24 at 16 dpi
DENV-4 97B BM5, 107 IR 36 at 8 dpi, 16 at 12 dpi, 28 at 16 dpi, 32 at 20 dpi; TR 0 at 8,12 and 16 dpi, 8 at 20 dpi
Townsville, Aus DENV-2 92T BM5, 106.4 IR 72 at 8 dpi, 90 at 8 dpi, 92 at 16 dpi; TR 0 at 8 dpi, 0 at 12 dpi, 28 at 16 dpi
DENV-4 97B BM5, 107 IR 12 at 8 dpi, 28 at 12 dpi, 40 at 16 dpi, 32 at 20 dpi; TR 0 at 8, 12 and 16 dpi, 16 at 20 dpi
Cairns, Aus DENV-2 92T BM5, 106.4 IR 80 at 8 dpi, 84 at 12 dpi, 80 at 16 dpi; 8 at 8 dpi, 4 at 12 dpi, 20 at 16 dpi
DENV-4 97B BM5, 107 IR 16 at 8 dpi, 28 at 12 dpi, 36 at 16 and 20 dpi; TR 0 at 8 and 12 dpi, 4 at 16 and 20 dpi
Huber et al., 200312 Ho Chi Minh City, (mosquitoes collected from 1975 to 1998) DENV-2, strain not defined BM, ntd IR 94.8 +/− 3.61
Ho Chi Minh City (mosquitoes collected from 1975 to 1998) DENV-2, strain not defined BM, ntd IR 97.7 +/− 2.39
Paea strain, Thaiti DENV-2, strain not defined BM, ntd IR 93.84 +/− 4.38
Lourenco-de-Oliveira et al., 2004 Belém, BR DENV-2 Bangkok 1974 BM, ntd IR 96.3
Ananindeua, BR DENV-2 Bangkok 1974 BM, ntd IR 94.23
Rio Branco, BR DENV-2 Bangkok 1974 BM, ntd IR 81.43
Porto Velho DENV-2 Bangkok 1974 BM, ntd IR 83.19
Boa Vista, BR DENV-2 Bangkok 1974 BM, ntd IR 95,75
Salvador, BR DENV-2 Bangkok 1974 BM, ntd IR 81.48
Sao Luis, BR DENV-2 Bangkok 1974 BM, ntd IR 97,38
Feira de Santana, BR DENV-2 Bangkok 1974 BM, ntd IR 74,74
Milha, BR DENV-2 Bangkok 1974 BM, ntd IR 25,79
Pacuja, BR DENV-2 Bangkok 1974 BM, ntd IR 73,62
Quixeramobin, BR DENV-2 Bangkok 1974 BM, ntd IR 82,10
Represa dp Cigano, BR DENV-2 Bangkok 1974 BM, ntd IR 98,24
Tingua, BR DENV-2 Bangkok 1974 BM, ntd IR 84,85
Higienopolis, BR DENV-2 Bangkok 1974 BM, ntd IR 75,32
Moqueta, BR DENV-2 Bangkok 1974 BM, ntd IR 93,40
Rocinha, BR DENV-2 Bangkok 1974 BM, ntd IR 92,86
Comendador Soares, BR DENV-2 Bangkok 1974 BM, ntd IR 91,15
Cariacica, BR DENV-2 Bangkok 1974 BM, ntd IR 81,81
Potim, BR DENV-2 Bangkok 1974 BM, ntd IR 83,62
Leandro Ferreira, BR DENV-2 Bangkok 1974 BM, ntd IR 85,95
Foz de Iguacu, BR DENV-2 Bangkok 1974 BM, ntd IR 62,43
Maringa, BR DENV-2 Bangkok 1974 BM, ntd IR 73,6
Campo Grande, BR DENV-2 Bangkok 1974 BM, ntd IR 72,73
Paea Lab. strain DENV-2 Bangkok 1974 BM, ntd IR 93,34 +/− 4.63
Paupy et al., 200312 Phon Penh City Center (Cambodia), mosquitoes collected in February DENV-2 from a hs sample collected in Bangkok Thai in 1974 BM3, 108.2 IR 79,39 +/− 11,01
Phon Penh City Center (Cambodia), mosquitoes collected in July DENV-2 from a hs sample collected in Bangkok Thai in 1974 BM3, 108.2 IR 77,76 +/− 8,31
Phon Penh City suburbs north (Cambodia), mosquitoes collected in February DENV-2 from a hs sample collected in Bangkok Thai in 1974 BM3, 108.2 IR 90,65 +/− 8,77
Phon Penh City suburbs west (Cambodia), mosquitoes collected in February DENV-2 from a hs sample collected in Bangkok Thai in 1974 BM3, 108.2 IR 87 +/− 4,82
Phon Penh City suburbs south (Cambodia), mosquitoes collected in February DENV-2 from a hs sample collected in Bangkok Thai in 1974 BM3, 108.2 IR 95,30 +/− 0.14
Paea strain, Thaiti DENV-2 from a hs sample collected in Bangkok Thai in 1974 BM3, 108.2 IR 78.52 +/− 7.64
Thongrungkiat et al., 2003 Chiang Rai, Thai DENV-1 16007 BM3, 108.1 IR 19.4
BM3, 1010 IR 48.7
DENV-2 16681 BM3, 108.1 IR 17.8
BM3, 1010 IR 25
DENV-3 16562 BM3, 108.1 IR 3.8
BM3, 1010 IR 19.7
DENV-4 1036 BM3, 108.1 IR 27.7
BM3, 1010 IR 54.8
Nakhon Phanom, Thai DENV-1 16007 BM3, 108.1 IR 16
BM3, 1010 IR 48.2
DENV-2 16681 BM3, 108.1 IR 15
BM3, 1010 IR 28
DENV-3 16562 BM3, 108.1 IR 4.3
BM3, 1010 IR 18.5
DENV-4 1036 BM3, 108.1 IR 15.6
BM3, 1010 IR 49.4
Satun, Thai DENV-1 16007 BM3, 108.1 IR 8.1
BM3, 1010 IR 43.8
DENV-2 16681 BM3, 108.1 IR 13.1
BM3, 1010 IR 27.6
DENV-3 16562 BM3, 108.1 IR 0.9
BM3, 1010 IR 11.1
DENV-4 1036 BM3, 108.1 IR 12.5
BM3, 1010 IR 54.5
Bennett et al., 20029 Hermosillo, Sonora, MX DENV-2 JAM1409 BM4, 107.5 to 108.5 IR 45
Guymas, Sonora, MX DENV-2 JAM1409 BM4, 107.5 to 108.5 TR 60
Culiacan, Sinaloa, MX DENV-2 JAM1409 BM4, 107.5 to 108.5 TR 80
Mazatlan, Sinaloa, MX DENV-2 JAM1409 BM4, 107.5 to 108.5 TR 65
Puerto Valarta, Jalisco, MX DENV-2 JAM1409 BM4, 107.5 to 108.5 TR 30
Manzanillo, Colima, MX DENV-2 JAM1409 BM4, 107.5 to 108.5 TR 55
Lazaro Cardenas, Michoacan, MX DENV-2 JAM1409 BM4, 107.5 to 108.5 TR 45, with a large standard deviation
Ixtapa Zihuatanejo, Guerrero, MX DENV-2 JAM1409 BM4, 107.5 to 108.5 TR 42, with a large standard deviation
Coyuca de Benitez, Guerrero, MX DENV-2 JAM1409 BM4, 107.5 to 108.5 TR 70
Puerto Excondido, Oaxaca, MX DENV-2 JAM1409 BM4, 107.5 to 108.5 TR 60
Tapachula, Chiapas, MX DENV-2 JAM1409 BM4, 107.5 to 108.5 TR 70 (two collections from Tapachula were tested giving one TR of 60, one of 80)
Chetumal, Quintana Roo, MX DENV-2 JAM1409 BM4, 107.5 to 108.5 TR 80
Cancun, Quintana Roo, MX DENV-2 JAM1409 BM4, 107.5 to 108.5 TR 70
Merida, Yucatan, MX DENV-2 JAM1409 BM4, 107.5 to 108.5 TR 69
Campeche, Campeche, MX DENV-2 JAM1409 BM4, 107.5 to 108.5 TR 42
Ciudad del Carmen, Campeche, MX DENV-2 JAM1409 BM4, 107.5 to 108.5 TR 42
Villahermosa, Tabasco, MX DENV-2 JAM1409 BM4, 107.5 to 108.5 TR 58
Moloacan, Veracruz, MX DENV-2 JAM1409 BM4, 107.5 to 108.5 TR 58
Miguel Aleman, Tamaulipas, MX DENV-2 JAM1409 BM4, 107.5 to 108.5 TR 60
Nuevo Ladero, Tamaulipas, MX DENV-2 JAM1409 BM4, 107.5 to 108.5 TR 48
Monterey, Nuevo Leon, MX DENV-2 JAM1409 BM4, 107.5 to 108.5 TR 56
Huston, TX DENV-2 JAM1409 BM4, 107.5 to 108.5 TR 40, with a great standard deviation
Tucson, Arizona DENV-2 JAM1409 BM4, 107.5 to 108.5 TR 68
Vazeille et al., 2001 Mahaleja, Madagascar DENV-2 Bangkok 1974 BM3, 108.2 IR 27.8
Jeffreville, Madagascar DENV-2 Bangkok 1974 BM3, 108.2 IR 32.5
Paea Lab. strain DENV-2 Bangkok 1974 BM3, 108.2 IR 94
Tran et al., 1999 Ho Chi Minh City DENV-2 Bangkok 1974 BM3, 108.2 IR 96,16 +/− 3.35
Watson & Kay, 199912 Queensland, Aus Lab. strain DENV-1 from hs of a patent in Townaville in 1990 BM6, 0–6–3,6 Log10 IR 31 +/− 23.34
DENV-2 from hs of a patent in Townaville in 1992 BM6, 1,2–4,2 Log10 IR 35.5 +/− 25.67
DENV-3 h87 BM6, 0,9–3,9 Log10 IR 42 +/− 27.72
DENV-4 h241 BM6, 0,6–3,6 Log10 IR 36 +/− 22,02
Jupp and Kemp, 199312 Empangeni, SA DENV-1 Cassim strain from Durban, SA BM3, 7,2 Log10 IR 100 at 8–10 dpi
Palm Beach, SA DENV-1 Cassim strain from Durban, SA BM, 6.1–7.1 Log10 IR 15, TR 100 at 17–19 dpi; IR 28, TR 50 at 16–17 dpi
DENV-2 BC 5007 strain from Taipei BM3, 7.2–7.9 Log10 IR 15.5 and TR 50 at 17–18 dpi; IR 25, TR 83 at 15 dpi
Durban, SA DENV-1 Cassim strain from Durban, SA BM3, 6.3–7.1 Log10 IR 62.8, TR 92 at 17–19 dpi; IR 43, TR 73 at 13–15 dpi
DENV-2 BC 5007 strain from Taipei BM, 7–7.5 Log10 IR 46, TR 75 at 14–15 dpi
Richards Bay, SA DENV-1 Cassim strain from Durban, SA BM3, 6.1–7.1 Log10 IR 38, TR 69.5 at 17–19 dpi,
DENV-2 BC 5007 strain from Taipei BM3, 7.2–7.5 Log10 IR 29.5; TR 69 at 14–20 dpi
Ndumu, SA DENV-1 Cassim strain from Durban, SA BM3, 6.3–7.1 Log10 IR 36.5; TR 75 at 18–19 dpi
DENV-2 BC 5007 strain from Taipei BM, 7.1 Log10 IR 41.67; TR 82 at 14–18 dpi
Skukuza, SA DENV-1 Cassim strain from Durban, SA BM3, 6.9–8.4 Log10 IR 12.5; TR 100 at 14–20 dpi;
DENV-2 BC 5007 strain from Taipei BM3, 7–7.9 Log10 IR 28; TR 66.5 at 16–19 dpi
Chen et al., 1993 Kaohsiung, southern Taiwan DENV-1 from a dengue patient during the dengue epideminc in Kaohsiung in 1987–1988 IT TR 50 at 14 dpi, 83.3 at 21 dpi
Bosio et al., 1998 San Juan, PR DENV-2PR-159, PR BM, ntd IR in midguts: 61
Aedes aegytpi formosus from Ibo village, Nigeria DENV-2PR-159, PR BM, ntd IR in midguts: 25
Mitchell et al., 1987 Rexville strain from PR DENV-1 1620, PR BM3, 6.6–9.2 Log10 IR 45 at 7 dpi, 605 at 14 dpi, TR 88
DENV-2 1615, PR BM3, 5.6–8.4 Log10 IR 25 at 7 dpi, 28.67 at 13 dpi, 56.4 1t 14 dpi, TR 74
DENV-3 1557, PR BM3, 6.3–8.4 Log10 IR 5 at 7 dpi, 58.2 at 14 dpi, TR 53
DENV-4 1632, PR BM3, 6.2–9.2 Log10 IR 0 at 7 dpi, 19.67 at 13 dpi, 63 at 14 dpi, TR 42
Boromisa et al., 1987 Lab. strain from Huston, TX DENV-1 YARU 40130, Fijii BM3, 8.3 Log10 IR 70 in midguts; 30 in whole body; TR 5
Rosen et al., 1985 Rockefeller strain DENV-1 Hawaii 1944 BM3, 107.8 IR 16.7
Niue strain from Niue Island DENV-1 Hawaii 1944 BM3, 107.8 IR 0
DENV-1 Malay-1 (Malaysia 1965) BM3, 107.8 IR 0
DENV-1 Malay-2 (Malaysia 1966) BM3, 107.8 IR 20
DENV-1 Thai (Bangkok, 1971) BM3, 107.8 IR 25
Rockefeller strain DENV-2 NG 1944 BM3, 107.8 IR 50
DENV-2 Thaiti 1971 BM3, 107.8 IR 45
Niue strain from Niue Island DENV-2 Thaiti 1971 BM3, 107.8 IR 13.6
Tong strain from Tonga DENV-2 Thaiti 1971 BM3, 107.8 IR 23.5
Rockefeller strain DENV-3 H87 Manila, Phi 1956 BM3, 107.8 IR 26.7
DENV-3 Manila Manila Phi 1965 BM3, 107.8 IR 34.6
DENV-3 Tahiti 1964 BM3, 107.8 IR 30.8
DENV-3 Thai, Bangkok Thai 1971 BM3, 107.8 IR 36.8
Trinidad strain from Trinidad DENV-3 Manila Manila Phi 1965 BM3, 107.8 IR 20
DENV-3 Tahiti 1964 BM3, 107.8 IR 22.2
DENV-3 Thai, Bangkok Thai 1971 BM3, 107.8 IR 71
Rockefeller strain DENV-4 H241 BM3, 107.8 IR 100–0 depending on viral dose inocula
2) ZIKV
Calvez et al. (2018) French Polynesia NC-2014-5132, NC BM, 107 TCID50/mL IR: 53 at 6 dpi; 94 at 9 dpi; 97 at 14 dpi, 89 at 21 dpi; TR 0 between 6 and 9 dpi; 24 at 21 dpi
NC IR: 88 at 6 dpi; 73 at 9 dpi; 77 at 14 dpi, 95 at 21 dpi; TR 0 at 6dpi, 3 at 9 dpi, 0 between 14 and 21 dpi
Samoa IR: 33 at 6 dpi; 23 at 9 dpi; 50 at 14 dpi, 38 at 21 dpi; TR 0 between 6 and 9 dpi; 17 at 14 dpi and 30 at 21 dpi
Main et al. (2018) Los Angeles, CA PRVABC59, PR BM, 5.4-6.4 log10 IR: 85 at 14 dpi; 96 at 21 dpi; DR 78 at 7-14 dpi, TR 65 at 14 dpi, 74 at 21 dpi
MA66, P6-740, Maylasia BM, 4.3-4.8 log10 IR: 86 at 14 dpi; 96 at 21 dpi; DR 79 at 7 dpi, 91 at 14 dpi, TR 53 at 14 dpi, 87 at 21 dpi
BR15, SPH2015, BR BM, 4.7 log10 IR: 90; DR: 90; TR: 75 at 14 dpi
Garcia-Luna et al. (2018)12 Apodaca, MX PRVABC59, PR BM, 1.5-1.8×106 IR 79 at 7 dpi; 84 at 14 dpi; DR 71 at 7 dpi, 80 at 14 dpi; TR 15 at 7 dpi; 33 at 14 dpi
San Nicolas, MX PRVABC59, PR BM, 4×105-2×107 IR 97 at 7 dpi; 93 at 14 dpi; DR 51 at 7 dpi, 88 at 14 dpi; TR 4 at 7 dpi; 27 at 14 dpi
Monterey, MX PRVABC59, PR BM, 8×105-4×107 IR 83 at 7 dpi; 63 at 14 dpi; DR 19 at 7 dpi, 45 at 14 dpi; TR 1 at 7 dpi; 14 at 14 dpi
Cd. Madero, MX PRVABC59, PR BM, 6.2-8×105 IR 53 at 7 dpi; 60 at 14 dpi; DR 28 at 7 dpi, 52 at 14 dpi; TR 7 at 7 dpi; 17 at 14 dpi
Poza Rica, MX PRVABC59, PR BM, 1.4x105x1.8×107 IR 100 at 7-14 dpi; DR 98 at 7 dpi, 100 at 14 dpi; TR 10 at 7 dpi; 52 at 14 dpi
Minatitlan, MX PRVABC59, PR BM, 6.2×105-1.6×106 IR 91 at 7dpi, 81 at 14 dpi; DR 72 at 7 dpi, 78 at 14 dpi; TR 10 at 7 dpi; 29 at 14 dpi
Coatzacoalcos, MX PRVABC59, PR BM, 1.4×105-1.7×106 IR 92 at 7dpi, 98 at 14 dpi; DR 73 at 7 dpi, 95 at 14 dpi; TR 24 at 7 dpi; 51 at 14 dpi
Merida, MX PRVABC59, PR BM, 8×105-4.4×107 IR 99 at 7dpi, 96 at 14 dpi; DR 74 at 7 dpi, 92 at 14 dpi; TR 10 at 7 dpi; 42 at 14 dpi
Mazatan, MX PRVABC59, PR BM, 1.12-4.4×107 IR 100 at 7-14dpi; DR 95 at 7 dpi, 100 at 14 dpi; TR 15 at 7 dpi; 23 at 14 dpi
Guerrero, MX PRVABC59, PR BM, 2×106-1.8×107 IR 98 at 7, 93 at 14dpi; DR 95 at 7 dpi, 93 at 14 dpi; TR 50 at 7 dpi; 42 at 14 dpi
Dodson et al. (2018) Rockefeller strain PRVABC59, PR BM, 2×108 IR: 40.67 +/− 19; TR 2.67 +/− 4.62
Roundy et al. (2017) Salvador, BR DAK AR 41525, S BM/murine2, 104-6 IR 100; TR100
FSS 13025, Cambodia BM/murine2, 104-6 IR 75; TR 0 murine: IR 100; TR 40
MEX1-7, MX BM, 2×108 IR 75; TR 0
Dominican Republic DAK AR 41525, S BM, 2×108 IR 100; TR100
FSS 13025, Cambodia BM, 2×108 IR 100; TR 18
MEX1-7, MX BM, 2×108 IR 90; TR 20
RioGrande Valley DAK AR 41525, S BM, 2×108 IR 100; TR 30
FSS 13025, Cambodia BM, 2×108 IR 40; TR 0
MEX1-7, MX BM, 2×108 IR 65; TR 0
Kenney et al. (2017) Poza Rica, MX, Lab. strain PRV ABC59 IT, 106 IR 100; TR 67
Heitmann et al., 2017 Bayer company, Lab. strain FB-GWUH-2016, Central America BM, 107 18 °C: IR 55; TR 0 27 °C: IR 49; TR 22
Fernandes et al. (2017) Rio de Janeiro, BR ZIKV strains from BR BM, 106.36 IR 68-100;
Guedes et al. (2017) Fernando de Noronha, BR BRPE 243/ 2015, BR BM, 106 IR 40
Recife, Lab. strain BRPE 243/ 2015, BR BM, 106 IR 44
Ciota et al. (2017) Poza Rica, MX CAM FSS130325, Cambodia BM, 106.6-7.7 IR 44; TR 33
HND 2016-19,563, Honduras BM, 106.6-7.7 IR 47; TR 36
Li et al. (2017)9 HK strain from mosquitoes collected in Hainan province, Chi SZ01/2016/Chi BM, 3×105 IR midguts: 80 at 2dpi, 80 at 4 dpi, 85 at 6 dpi, 90 at 8 dpi, 100 at 10 dpi, 90 at 12 dpi, 100 at 16,18 and 20 dpi
IR salivary glands: 58 at 2dpi, 78 at 4 dpi, 85 at 6 dpi, 90 at 8 dpi, 90 at 10 dpi, 100 at 12 dpi, 90 at 16,100 at 18 and 20 dpi
RL strain from mosquitoes collected in Yunnan province, Chi SZ01/2016/Chi BM, 3×105 IR midguts 100 at 2, 4, 6, 8, 10, 12, 16,18 and 20 dpi
IR salivary glands: 60 at 2dpi, 80 at 4 dpi, 100 at 6 dpi, 90 at 8 dpi, 100 at 10, 12, 16, 18 and 20 dpi
Ryckebusch et al. (2017) Paea strain, Thaiti PF-25013-18 BM2, 2.5×107 IR midguts 100 from 3 to 10 dpi, 85 at 13 dpi
IR in salivary glands 60 at 5, 6 and 8 dpi, 80 at 10 dpi and 7 at 14 dpi
TR 11 at 8 dpi, 33 at 10 dpi, 16 at 14 dpi and 6.7 at 17 dpi
Costa-da-Silva et al. (2017) Rockefeller lab. Strain ZIKVBR Isolated from a clinical case BM; 2.2×106 IR 95 in body and heads at 7 and 14 dpi; TR 10 at 7 dpi; 38 at 14 dpi
HWE Lab. strain BM; 2.2×106 IR 60 in body, 50 in heads at 7 dpi; 65 in body and head at 14 dpi; TR 0 at 7dpi, 35 at 14 dpi
RED lab. Strain BM; 2.2×106 IR 95 in body and 70 heads at 7 dpi; 95 in body and heads at 14 dpi; TR 0 at 7 dpi, 5 at 14 dpi
Weger-Lucarelli et al. (2016) Poza Rica, MX PRV ABC59, PR BM, fresh 106.3 IR 95, TR 70
PRV ABC59, PR BM, frozen 4 h 106.3 IR 95, TR 65
PRV ABC59, PR BM, frozen 1 week 106.3 IR 60, TR 22
DAKAR 41525, S BM, frozen 07.2 IR 75, TR 55
MR 766, Uganda BM, frozen 107.2 IR 58, TR 37
Richard et al. (2016a) Tahiti 2014 PF13/2511013-18 Polynesia BM4, 107 BM: IR 85; TR 36
Hall-Mendelin et al. (2016) Queensland, Aus MR 766, Uganda BM4, 106.7 BM: IR 57; TR 27
Di Luca et al. (2016) MX, Lab. strain H/PF/2013 French Polynesia BM, 106.4 IR 40, TR 40
Dutra et al. (2016) Urca, Rio de Janeiro, BR BRPE 243/2015 BR BM, fresh 5×106 IR 100, TR 100
Alto et al. (2017) Black eyed Liverpool, Lab. strain PRV ABC59 Murine 106.8 IR 100; TR 24
Boccolini et al. (2016) Reynosa, MX, Lab. strain H/PF/2013 French Polynesia BM, 106.46 IR 50; TR 38
Chouin-Carneiro et al. (2016) FG NC-2014-5132, NC BM4, 107 7 dpi: IR 100, TR 0
Guadeloupe NC-2014-5132, NC BM4, 107 7 dpi: IR 87; TR 0
Martinique NC-2014-5132, NC BM4, 107 7 dpi I: IR 90; TR 0
Orlando, FL NC-2014-5132, NC BM4, 107 7 dpi: IR 93; TR nd
Tubiacanga, BR NC-2014-5132, NC BM4, 107 7 dpi: IR 83; TR nd
Li et al. (2012) Singapore MR 766, Uganda BM4, 107 BM: IR 100; TR 100
Diagne et al. (2015)13 Dakar, S, domestic ArD 128,000 and 132,912, Kedougou BM 6.4-7.6 log10 IR+, DR+, TR 0
Kedougou, S, sylvatic ArD 128,000 and 132,912, Kedougou BM 6.4-7.6 log10 IR+, DR+, TR 0
Cornet and Robin (1979) S-1971, Lab. strain ArD 24,280, S IT dose unknown 7-28 dpi TR 91
Boorman and Porterfield (1956) Nigeria, Lab. strain MR 766, Uganda BM, 106.7 LD50 60 dpi IR 100; TR 50
3)YFV
Couto-Lima et al. (2017)12 Goiania, BR 74,018-1D from BR BM, 106 IR 0 at 3dpi, 〰 30 at 7dpi, 〰 80 at 14 dpi, 〰 70 at 14 dpi
4408-1E from BR BM, 106 IR 0 at 3dpi, 〰 25 at 7dpi, 〰 78 at 14 dpi, 〰 10 at 14 dpi
S-79 from Senegal BM, 106 IR 0 at 3dpi, 〰 30 at 7dpi, 〰 80 at 14 dpi, 0 at 14 dpi
74,018-1D from BR BM, 106 TR 0 at 3dpi, 0 at 7dpi, 〰 18 at 14 dpi, 0 at 14 dpi
4408-1E from BR BM, 106 TR 0 at 3dpi, 0 at 7dpi, 〰 18 at 14 dpi, 58 at 14 dpi
S-79 from S BM, 106 TR 0 at 3dpi, 0 at 7dpi, 0 at 14 dpi, 0 at 14 dpi
Dickson et al. (2014) Fatick BA-55- West African Genyotype I, Nigeria BM, 106 IR 59
Fatick DAK -1279- West African Genyotype II, S BM, 7.9×105 IR 17
Bignona BA-55- West African Genyotype I, Nigeria BM, 106 IR 13
Bignona DAK -1279- West African Genyotype II, S BM, 6.1×107 IR 33
Richard Toll BA-55- West African Genyotype I, Nigeria BM, 2×106 BM, 7.9×105 IR 10
Richard Toll DAK -1279- West African Genyotype II, S IR 57
Goudiry BA-55- West African Genyotype I, Nigeria BM, 106 IR 0
Goudiry DAK -1279- West African Genyotype II, S BM, 7.9×105 IR 10
Ae aegypti formosus PK10, S, sylvatic BA-55- West African Genyotype I, Nigeria BM, 2×105 IR 0
Ae aegypti formosus PK10, S, sylvatic DAK -1279- West African Genyotype II, S BM, 7.9×105 IR 10
Ae aegypti formosus PK10, S, sylvatic BA-55- West African Genyotype I, Nigeria BM, 106 IR 3
Ae aegypti formosus PK10, S, sylvatic DAK -1279- West African Genyotype II, S BM, 7.9×105 IR 22
Mont Rolland BA-55- West African Genyotype I, Nigeria BM, 2×106 IR 0
Mont Rolland DAK -1279- West African Genyotype II, S BM, 7.9×105 IR 20
Rufisque BA-55- West African Genyotype I, Nigeria BM, 106 IR 0
Rufisque DAK -1279- West African Genyotype II, Senegal BM, 7.9×105 IR 11
Ellis et al. (2012) Nairobi, Kenya East African genotype (Sudan 2003) BM, 6.7-7.5 log10 IR 7
Mariakani, Kenya East African genotype (Sudan 2003) BM, 6.7-7.5 log10 IR 41
Kerio Valley, Kenya East African genotype (Sudan 2003) BM, 6.7-7.5 log10 IR 11
Kakamega, Kenya East African genotype (Sudan 2003) BM, 6.7-7.5 log10 IR 23
van den Hurk et al. (2011) Cairns, Aus African strain BA-55 (Nigeria 1955) BM4, 107.2 IR 80, TR 52
South American strain, Cinetrop 28 (OBS 7549) Bolivia 1999 BM4, 106.7 IR 64, TR 64
Asibi strain BM4, 108 IR 92, TR 80
Townsville, Aus African strain BA-55 (Nigeria 1955) BM4, 107.2 IR 72, TR 60
South American strain, Cinetrop 28 (OBS 7549) Bolivia 1999 BM4, 106.7 IR 36, TR 28
Asibi strain BM4, 108 IR 96, TR 96
RexD strain African strain BA-55 (Nigeria 1955) BM4, 107.2 IR 82, TR 64
South American strain, Cinetrop 28 (OBS 7549) Bolivia 1999 BM4, 106.7 IR 40, TR 32
Asibi strain BM4, 108 IR 76, TR 64
Johnson et al. (2002) Santos, Brazil no. 71528 MG2001, from BR BM, 7-7.8 log10 IR 35, TR 25.5
Lourenco-de-Oliveira et al. (2002) Milhã, BR FIOCRUZ 74018/MG/01 BM3, 108.7 IR 0
Comendador Soares, BR FIOCRUZ 74018/MG/01 BM3, 108.7 IR 0.9
Quixeramobim, BR FIOCRUZ 74018/MG/01 BM3, 108.7 IR 1.7
Rocinha, BR FIOCRUZ 74018/MG/01 BM3, 108.7 IR 3.3
Tinguá, BR FIOCRUZ 74018/MG/01 BM3, 108.7 IR 4.9
Pacujá, BR FIOCRUZ 74018/MG/01 BM3, 108.7 IR 5.6
Salvador, BR FIOCRUZ 74018/MG/01 BM3, 108.7 IR 6.3
Higienópolis, BR FIOCRUZ 74018/MG/01 BM3, 108.7 IR 6.7
Moquetá, BR FIOCRUZ 74018/MG/01 BM3, 108.7 IR 7.6
Feira de Santana, BR FIOCRUZ 74018/MG/01 BM3, 108.7 IR 10.6
Rio Branco, BR FIOCRUZ 74018/MG/01 BM3, 108.7 IR 11.1
Leandro Ferreira, BR FIOCRUZ 74018/MG/01 BM3, 108.7 IR 12.0
Cariacica, BR FIOCRUZ 74018/MG/01 BM3, 108.7 IR 12.6
Boa Vista, BR FIOCRUZ 74018/MG/01 BM3, 108.7 IR 12.9
Represa do Cigano, BR FIOCRUZ 74018/MG/01 BM3, 108.7 IR 16.1
São Luis, BR FIOCRUZ 74018/MG/01 BM3, 108.7 IR 19.6
Maringá, BR FIOCRUZ 74018/MG/01 BM3, 108.7 IR 22.7
Porto Velho, BR FIOCRUZ 74018/MG/01 BM3, 108.7 IR 24.4
Campo Grande, BR FIOCRUZ 74018/MG/01 BM3, 108.7 IR 25
Potim, BR FIOCRUZ 74018/MG/01 BM3, 108.7 IR 27.1
Belém, BR FIOCRUZ 74018/MG/01 BM3, 108.7 IR 33.9
Ananindeua, BR FIOCRUZ 74018/MG/01 BM3, 108.7 IR 46.4
Foz do Iguaçu, BR FIOCRUZ 74018/MG/01 BM3, 108.7 IR 48.6
Phnom Penh, Cambodia FIOCRUZ 74018/MG/01 BM3, 108.7 IR 64.4
Ho Chi Min FIOCRUZ 74018/MG/01 BM3, 108.7 IR 48.05
Maracay, Venezuela FIOCRUZ 74018/MG/01 BM3, 108.7 IR 13.6
West Palm Beach, FL FIOCRUZ 74018/MG/01 BM3, 108.7 IR 24.8
Ae. aegypti formosus Boulbinet Guinea FIOCRUZ 74018/MG/01 BM3, 108.7 IR 3.3
Mitchell et al. (1987) Rexville strain from PR 788,379 BM, 5.0-6.7 Log10 IR 61 at 11 dpi, 80 at 14 dpi; TR 42 at 11 dpi, 38 at 14 dpi
Wallis et al. (1985) Soufriere, Dominica Asibi strain BM, ntd IR 17,17 +/− 13,50
Tabachnick et al. (1985) West Africa Sylvan, Dakar S, lab. Strain Asibi strain BM, ntd IR 11
West Africa Sylvan, N'Gove S, lab. Strain Asibi strain BM, ntd IR 7
West Africa Sylvan, Gambia, lab. Strain Asibi strain BM, ntd IR 27
East Africa Sylvan, Kampala Uganda, lab. Strain Asibi strain BM, ntd IR 8
Asibi strain BM, ntd IR 34
East Africa Sylvan, Kombeni, Kenya; lab. Strain
East Africa Domestic, Kwa Dzivo Kenya; isofemale lines Asibi strain BM, ntd IR 57
East Africa Domestic, Majengo Kenya; isofemale lines Asibi strain BM, ntd IR 29
Asia-Pacific Domestic Bangalore India; lab. Strain Asibi strain BM, ntd IR 23
Asia-Pacific Domestic Colombo Sri Lanka; lab. Strain Asibi strain BM, ntd IR 21
Asia-Pacific Domestic Djakarta Java; lab. Strain Asibi strain BM, ntd IR 32
Asia-Pacific Domestic Karachi Pakistan; lab. Strain Asibi strain BM, ntd IR 30
Asia-Pacific Domestic Thai, Amphur strain Asibi strain BM, ntd IR 28
Asia-Pacific Domestic Fiji; lab. Strain Asibi strain BM, ntd IR 22
Domestic Austin, TX; isofemale lines Asibi strain BM, ntd IR 29
Domestic Galveston, TX; lab. Strain Asibi strain BM, ntd IR 16
Domestic Huston, TX; lab. Strain Asibi strain BM, ntd IR 21
Domestic Welasco, Texas USA; lab. Strain Asibi strain BM, ntd IR 15
Domestic Victoria, MX; isofemale lines Asibi strain BM, ntd IR 20
Domestic Abbeville, Luisiana USA; lab. Strain Asibi strain BM, ntd IR 12
Domestic Beamont, TX; lab. Strain Asibi strain BM, ntd IR 26
Domestic Vero Beach, FL; field Asibi strain BM, ntd IR 41
Domestic Esquintla, Guatemala; isofemale lines Asibi strain BM, ntd IR 2
Domestic Malaga, Colombia; field Asibi strain BM, ntd IR 46
Domestic Santa Cruz, Bolivia; isofemale lines Asibi strain BM, ntd IR 31
Domestic Trinidad, West Indies; isofemale lines Asibi strain BM, ntd IR 42
Domestic Arecibo, Puerto Rico; lab. Strain Asibi strain BM, ntd IR 34
Domestic Limestone Bay, Anguilla; field Asibi strain BM, ntd IR 39
Domestic Plymouth, Montserrat; field Asibi strain BM, ntd IR 53
4) CHIKV14
Agha et al. (2017) Mombasa, Kenya Lamu001 strain of and East/Central/South Africa lineage BM, 105.6 IR 0 at 5-7 dpi
BM, 105.9 IR 6 at 5-7 dpi and 17 at 9 dpi
BM, 106.9 IR 62 at 5-7 dpi
BM, 107.5 IR 100 at 5-7 dpi and 75 at 14 dpi
Kisumu, Kenya BM, 105.6 IR 0 at 5-7 dpi and 0 at 14 dpi
BM, 105.9 IR 20 at 5-7 dpi; 5 at 9 dpi and 6 at 14 dpi
BM, 106.9 IR 40 at 5-7 dpi; 50 at 9 dpi and 63 at 14 dpi
Nairobi, Kenya BM, 105.6 IR 0 at 5-7 dpi and 17 at 14 dpi
BM, 105.9 IR 7 at 5-7 dpi and 10 at 9 dpi
BM, 106.9 IR 50 at 5-7 dpi and 57 at 9 dpi
BM, 107.5 IR 71 at 5-7 dpi and 89 at 14 dpi
Alto et al. (2017) Indian River/ St. Lucie County, FL BM, 8 log10 IR in legs 37 at 2dpi, 71 at 5 dpi, 28 at 12 dpi; TR 35 at 2 dpi, 66 at 5 dpi, 24 at 12 dpi
Monroe County, FL BM, 8 log10 IR in legs 90 at 2dpi, 20 at 5 dpi, 54 at 12 dpi; TR 83 at 2 dpi, 18 at 5 dpi, 50 at 12 dpi
Manatee county, FL BM, 8 log10 IR in legs 71 at 2dpi, 68 at 5 dpi, 60 at 12 dpi; TR 58 at 2 dpi, 63 at 5 dpi, 51at 12 dpi
Dominican Repuublic BM, 8 log10 IR in legs 35 at 2dpi, 22 at 5 dpi, 18 at 12 dpi; TR 17 at 2 dpi, 19 at 5 dpi, 15 at 12 dpi
Ngoagouni et al. (2017) Bangui, Central African Republic ArB10262 BM; 108 IR 50 at 7 dpi, 27 at 14 dpi, TR 0 at 7 dpi, 28 at 14 dpi
Mbaika et al. (2016) Coastal Kenya South/Central Africa and Indian Ocean Genotype (Group III), subgroup IIIa and b BM; 7.9×105 IR tested in Midgut at 26 °C 26.41 7dpi; 33.96 10 dpi, 39.62 13 dpi;
IR tested in Midgut at 32 °C 26.41 7dpi; 33.96 10 dpi, 39.62 13 dpi;
IR tested in legs at 26 °C 17.9 7dpi; 25.5 10 dpi, 17 13 dpi;
IR tested in legs at 32 °C 6.8 7dpi; 20.4 10 dpi, 29.1 13 dpi;
IR tested in heads at 26 °C 10.4 7dpi; 2.8 10 dpi, 2.8 13 dpi;
IR tested in heads at 32 °C 2.9 7dpi; 16.5 10 dpi, 26.2 13 dpi;
Western Kenya South/Central Africa and Indian Ocean Genotype (Group III), subgroup IIIa and b BM; 7.9×105 IR tested in Midgut 26 °C 7.55 7dpi; 5,66 10 dpi, 18,88 13 dpi;
IR tested in Midgut 32 °C 33,02 7dpi; 24,53 10 dpi, 24,53 13 dpi;
IR tested in legs at 26 °C 26.5 7dpi; 11.8 10 dpi, 20.6 13 dpi;
IR tested in legs at 32 °C 28.7 7dpi; 17.2 10 dpi, 26.4 13 dpi;
IR tested in heads at 26 °C 26.5 7dpi; 17.6 10 dpi, 20.6 13 dpi;
IR tested in heads at 32 °C 25.3 7dpi; 8 10 dpi, 23 13 dpi;
Richard et al. (2016b) districts of Toahotu, Thaiti Island PF14/300914-109 BM4, 7 log10 TCID50/mL IR 78 at 6 dpi, 87 at 9 dpi, 90 at 14 dpi, 80 at 21 dpi
TR 5 at 2 dpi, 18 at 6 dpi, 34 at 9 dpi, 49 at 14 dpi abd 53 at 21 dpi
Vega-Rua et al. (2014) Vero Beach, FL CHIKV 06.21 BM 107.5 IR 100 at 7 dpi, 100 at 10 dpi
CHIKV 05.115 BM 107.5 IR 100
Chiapas, MX CHIKV 06.21 BM 107.5 IR 96.7 at 7 dpi, 93.3 at 10 dpi
CHIKV 05.115 BM 107.5 IR 96.7 at 7 dpi, 100 at 10 dpi
Panama CHIKV 06.21 BM 107.5 IR 96.7 at 7 dpi, 100 at 10 dpi
CHIKV 05.115 BM 107.5 IR 96.7 at 7 and 10 dpi
NC/2011-568 BM 107.5 IR 100 at 7 and 10 dpi
Delta Amacuro, Venezuela CHIKV 06.21 BM 107.5 IR 100 at 7 and 10 dpi
CHIKV 05.115 BM 107.5 IR 100 at 7 and 10 dpi
Tumbes, Peru CHIKV 06.21 BM 107.5 IR 100 at 7 and 10 dpi
Punchana, Peru CHIKV 06.21 BM 107.5 IR 100 at 7 and 10 dpi
CHIKV 05.115 BM 107.5 IR 100 at 7 and 10 dpi
Manaus, BR CHIKV 06.21 BM 107.5 IR 100 at 7 and 10 dpi
NC/2011-568 BM 107.5 IR 100 at 7 and 10 dpi
Santarem, BR CHIKV 06.21 BM 107.5 IR 100 at 7 and 10 dpi
Parnamirin, BR CHIKV 06.21 BM 107.5 IR 100 at 7 and 10 dpi
Campos Belos,BR CHIKV 06.21 BM 107.5 IR 100 at 7 and 10 dpi
Campos Grande, BR CHIKV 06.21 BM 107.5 IR 100 at 7 and 10 dpi
CHIKV 05.115 BM 107.5 IR 100 at 7 and 10 dpi
Jurujuba, BR CHIKV 06.21 BM 107.5 IR 100 at 7 and 10 dpi
CHIKV 05.115 BM 107.5 IR 100 at 7 and 10 dpi
Paqueta, BR CHIKV 06.21 BM 107.5 IR 100 at 7 and 10 dpi
CHIKV 05.115 BM 107.5 IR 100 at 7 and 10 dpi
Vaz Lobo, BR CHIKV 06.21 BM 107.5 IR 100 at 7 dpi; 96,7 at 10 dpi
Belford Roxo, BR CHIKV 06.21 BM 107.5 IR 100 at 7 and 10 dpi
Santos, BR CHIKV 06.21 BM 107.5 IR 93.3 at 7 dpi, 100 at 10 dpi
Monteagudo, Bolivia CHIKV 06.21 BM 107.5 IR 100 at 7 and 10 dpi
CHIKV 05.115 BM 107.5 IR 100 at 7 and 10 dpi
Salto del Guaira, Paraguay CHIKV 06.21 BM 107.5 IR 100 at 7 and 10 dpi
Asuncion, Paraguay CHIKV 06.21 BM 107.5 IR 100 at 7 and 10 dpi
CHIKV 05.115 BM 107.5 IR 96.7 at 7 dpi, 93.3 at 10 dpi
Salto, Uruguay CHIKV 06.21 BM 107.5 IR 100 at 7 and 10 dpi
CHIKV 05.115 BM 107.5 IR 100 at 7 and 10 dpi
Corrientes, Argentina CHIKV 06.21 BM 107.5 IR 100 at 7 and 10 dpi
CHIKV 05.115 BM 107.5 IR 100 at 7 dpi, 96.7 at 10 dpi
Buenos Aires, Argentina CHIKV 06.21 BM 107.5 IR 100 at 7 dpi, 96.7 at 10 dpi
CHIKV 05.115 BM 107.5 IR 96.6 at 7 dpi, 100 at 10 dpi
NC/2011-568 BM 107.5 IR 96.9 at 7 dpi, 90 at 7 dpi
Dupont-Rouzeyrol et al. (2012) Noumea, NC, mosquitoes had a 92% susceptibility to pyrethroids (pop 163/11) NC/2011-568 BM 107.5 IR 53.3 at 3 dpi; 54.5 at 8 dpi; 66.7 at 14 dpi
Noumea, New Caledonia, mosquitoes had a 85% susceptibility to pyrethroids (pop 174/11) BM 107.5 IR 50 at 3 dpi; 64.3 at 8 dpi; 20 at 14 dpi
Noumea Laboratory strain, New Caledonia (pop 282/10) BM 107.5 IR 40 at 3 dpi; 58.8 at 8 dpi; 50 at 14 dpi
Noumea, NC, mosquitoes had a 92% susceptibility to pyrethroids (pop 163/11) CHIKV-RE from Reunion Island (2005), also known as CHIKV 06.21 BM 107.5 IR 33.3 at 3 dpi; 57.1 at 8 dpi; 75 at 14 dpi
Noumea, NC, mosquitoes had a 85% susceptibility to pyrethroids (pop 174/11) BM 107.5 IR 73.3 at 3 dpi; 46.2 at 8 dpi; 90 at 14 dpi
Noumea Lab.strain, NC(pop 282/10) BM 107.5 IR 40 at 3 dpi; 57.1 at 8 dpi; 66.7 at 14 dpi
Girod et al. (2011)15 Pointe a Pitre, Carenage, Guadaloupe CHIKV 06.21 BM, 107.5 IR 98 at 14 dpi in 2008; 96.6 at 7 dpi and 100 at 14 dpi in 2009
Petit bourg, Prise d'eau, Guadalupe CHIKV 06.21 BM, 107.5 IR 95.8 at 14 dpi in 2008; 97.9 at 14 dpi in 2009
Fort de France, Ermitage, Martinique CHIKV 06.21 BM, 107.5 IR 98.9 at 14 dpi in 2008; 100 at 7 dpi and 96.8 at 14 dpi in 2009
Robert, Cafe, Martinique CHIKV 06.21 BM, 107.5 IR 97.4 at 14 dpi in 2008; 88.9 at 7 dpi and 93.4 at 14 dpi in 2009
Cayenne, Centre Ville FG CHIKV 06.21 BM, 107.5 IR 100 at 14 dpi in 2008; 97.5 at 7 dpi and 95.5 at 14 dpi in 2009
Cayenne, Madeleine, FG CHIKV 06.21 BM, 107.5 IR 98.8 at 14 dpi in 2008; 94.7 at 7 dpi and 98.5 at 14 dpi in 2009
Pesko et al. (2009) Palm Beach, FL CHICK LR2006-OPY1, La Reunion Island BM, 6.1 log10 IR at 6 dpi 18.8 and 57.7 for mosquitoes feeding on pletdgets or water jackets membranes, respectively
BM, 5.2 log10 IR at 6 dpi 4.5 and 23.8 for mosquitoes feeding on pletdgets or water jackets membranes, respectively
BM, 4.4 log10 IR at 6 dpi 0 and 3.1 for mosquitoes feeding on pletdgets or water jackets membranes, respectively
BM, 3.6 og10 IR at 6 dpi 0 and 0 for mosquitoes feeding on pletdgets or water jackets membranes, respectively results
5) dual-infections
Rückert et al. (2017)16 Poza Rica, Mexico CHIKV (strain 99,659) BM 3.1×104-1.9×105 IR 87; TR 20 at 3dpi, 30 at 7 dpi, 60 at 14 dpi
DENV-2 (strain Merida) BM 3×103-7.4×105 IR 87; TR 0 at 3 dpi, 15 at 7 dpi, 20 at 14 dpi
ZIKV (strain PRVABC59) BM 1.7×104-5.4×105 IR 48; TR 0 at 3 dpi, 8 at 7 dpi, 40 at 14 dpi
CHIKV (strain 99,659) + DENV-2 (strain Merida) BM, as single IR CHIKV 87; DENV-2 85; TR at 3 dpi CHIKV 10; DENV 0; at 7 dpi CHIKV 38; DENV 10; at 14dpi CHIKV 30, DENV 18
CHIKV (strain 99,659) + ZIKV (strain PRVABC59) BM, as single IR CHIKV 90; ZIKV 45; TR at 3 dpi CHIKV 28; ZIKV 5; at 7 dpi CHIKV 45; ZIKV 8; at 14dpi CHIKV 40, ZIKV 38
ZIKV (strain PRVABC59) + DENV-2 (strain Merida) BM, as single IR ZIKV 50; DENV-2 80; TR at 3 dpi DENV 028; ZIKV 0; at 7 dpi DENV 20; ZIKV 0; at 14dpi DENV 38, ZIKV 20
Göertz et al. (2017) Rockefeller strain CHIKV strain 37,997 BM 2×105 IR 47.9, TR 10.4
BM 2×106 IR 66.7, TR 5.9
BM 2×107 IR 81.2, TR 21.2
ZIK Suriname strain 011 V-01621 BM 2×105 IR 65.3, TR 34.7
BM 2×106 IR 92.2, TR 68.6
BM 2×107 IR 100, TR 68.3
CHIKV (strain 37,997) + ZIKV Suriname strain BM, as single IR 84.4; TR 11.5
6) infections with arboviruses other than DENVs, YFV, ZIKV and CHIKV
Wiggins et al. (2018)12 Miami, FL Mayaro virus, Tridinad strain TRVL 4675 BM 7.5 log10 IR 65 at 6 dpi; 80 at 6 dpi; 70 at 9-12 dpi; DR 44 at 3 dpi; 60 at 6 dpi; 80 at 9 dpi-12 dpi; TR < 10 at 3-9 dpi; 25 at 12 dpi
Wang et al. (2012) Haikou strain, Chi Western equine encephalomyelitis virus (WEEV), McMillian strain BM, ntd IR 25; TR 45
Long et al. (2011) Iquitos, Peru Maroyo virus, strain IQT4235 BM, 5.59-7.34 Log10 IR 46.67±21.13; TR 83 +/− 23.44
BM, 5.57-3.36 Log10 IR 0.46 +/− 1.13;
Turell et al. (2007) Kenya, collected as eggs in 1982 Rift Valley Fever (RVFV) ZH501 from an Egyptian patient BM, 〰107-7.8 IR 100 at 3-10 dpi; 33 at 11-16 dpi
Rift Valley Fever ZH501 from an Egyptian patient BM, 〰10 > 8 IR 85 at 3-10 dpi; 75 at 11-16 dpi
Turell et al. (2001) Rockefeller strain West Nile virus Crow 397-99 BM 107.2 IR 16, TR < 16
Kay et al. (1979) Townsville colony, from northern Queesland in 1957 Sindbis MRM39
Getah N544 BM, 4-6.5 Log ID50 IR 64, TR 28.5, EIP 20
Ross River T78 BM, 4.9 Log ID50 IR 100, TR 69, EIP 12
Murray Valley Encephalitis MRM66 BM, 5.1 Log ID50 IR 96, TR 95, EIP 7-10
Kunji MRM16 BM, > 6.5 Log ID50 IR 46, TR 38, EIP 20-27
Kokobera MRM32 BM, 4.2 Log ID50 IR 100, TR 100, EIP 12
Edge Hill C281 BM, 2.7 Log ID50 IR 89, TR 80, EIP 20
Alfuy MRM3929 BM, > 5.5 Log ID50 IR 47, TR 21, EIP 10-15
Corriparta MRM1 BM, 2.1-2.9 Log ID50 IR 100, TR 5, EIP 10-15
Belmont Ch9824 BM, ntd IR 0, TR 0
Ngaingan MRM14556 BM, ntd IR 10, TR 0
CHIKV BKMS 459/64 BM, 4.7 Log ID50 IR 71, TR 57, EIP 15
Kramer and Scherer (1976) Laboratory strain Venezuelan Encephalitis virus, epizootic strain subytoe I, variety B, 69TI597 IT or BM TR 60 at 14 dpi, 100 at 17 dpi, 50 at 21 and 27 dpi
Venezuelan Encephalitis virus, enzootic strain subytoe I, variety E, 63Z1 IT or BM TR 0 at all time points

Abbreviations: BM, mosquitoes offered an infectious blood-meal; IT, mosquitoes were infected by intrathoracic inoculation; dpi, days post infection; IR, percentage of engorged females with viral particles in the head, legs and/or salivary glands; TR, transmission rate calculated as percentage of engorged females with viral particles in the saliva at 14 dpi, unless otherwise stated; PFU, plaque forming units, FFU, fluorescent focus unit, LD50, 50 infectious dose; TCID50, 50 tissue culture infectious dose; MID50, mosquito infectious dose for 50 of Ae. aegypti individuals; EIP, extrinsic incubation period; MX, Mexico; NC, New Caledonia; Col, Colombia; Viet, Vietnam; NG, New Guinea; FG, French Guiana; Thai, Thailand; S, S; PR, PR; BR, Brazil; Aus, Australia; Chi, China; Philippines, Phi; FL, Florida; South Africa, SA; Texas, TX; California, CA; isol., isolate; human serum, hs; lab. Strain, laboratory strain.

1

PFU/ml unless otherwise stated

2

FFU/ml

3

MID50/ml

4

TCID50/mL

5

CCID50/ml

6

PFU ingested per mosquito

7

expressed in unless otherwise stated

8

mosquitoes were tested for infections within the 9th generation after laboratory colonization

9

Infection and transmission rates reported here were extrapolated from a figure

10

wild-caught mosquitoes were adapted to the laboratory and tested at generation F10-15

11

Infection rates for DENV2 AdR 140,875 are mean over two infections experiments

12

results are mean over different experiments

13

mosquitoes were infected by all viruses strains and dissemination was studied for both strains

14

CHIKV 06.21 is the strain with the E1-226 V mutation and CHIKV 05.115 is the strain with the E1-226A mutation

15

experiments were carried out in two consecutive years (2008 and 2009); in 2009, two different concentrations of CHIKV were compared for infection rates at 7 dpi; only data for the highest concentration are shown here

16

mosquitoes of the F12_F14 after laboratory colonization were used in experimental infections.