TABLE 5.

Risk of requiring intensive care and mortality for patients hospitalised in France for COVID-19 (1 March 2020 to 30 April 2020) according to chronic respiratory disease (CRD) (disjunctive variables using prioritisation^#)

	ICU		Death
	OR (95% CI)	Adjusted OR (95% CI)	OR (95% CI)	Adjusted OR (95% CI)
No CRD	1	1	1	1
CF	0.63 (0.15–2.73)	0.60 (0.1–2.60)
Lung cancer	0.78 (0.64–0.94)¶	0.77 (0.63–0.94)¶	3.64 (3.20–4.14)	3.67 (3.20–4.21)
COPD	1.47 (1.37–1.58)	1.16 (1.07–1.26)	1.72 (1.61–1.84)	1.14 (1.06–1.22)
Asthma	1.35 (1.23–1.48)	1.23 (1.12–1.36)	0.51 (0.45–0.58)¶	0.82 (0.71–0.94)¶
Pulmonary sarcoidosis	2.94 (2.07–4.19)	2.65 (1.83–3.84)	1.38 (0.92–2.09)	2.11 (1.36–3.26)
ILDs	2.77 (2.47–3.11)	2.42 (2.14–2.72)	1.41 (1.24–1.61)	1.20 (1.05–1.38)
Emphysema	2.09 (1.78–2.45)	1.83 (1.56–2.16)	1.18 (0.99–1.42)	1.01 (0.83–1.22)
Sleep apnoea	2.74 (2.52–2.98)	1.39 (1.27–1.53)	1.12 (1.02–1.25)	0.95 (0.85–1.06)
Pulmonary hypertension	1.97 (1.46–2.65)	1.73 (1.27–2.37)	2.01 (1.50–2.68)	1.24 (0.91–1.67)
CRF	1.18 (0.94–1.49)	1.03 (0.81–1.30)	2.10 (1.74–2.54)	1.30 (1.06–1.59)

Odds ratios adjusted on obesity, diabetes, hypertension, heart failure, atherosclerotic heart disease, sex and age as a continuous variable. ICU: intensive care unit; CF: cystic fibrosis; COPD: chronic obstructive pulmonary disease; ILD: interstitial lung disease; CRF: chronic respiratory failure. ^#: each CRD patient was classified in only one single CRD category (when there were several CRD codes on the discharge abstract of a patient, we decided to prioritise in order to retain only one, using the following order: CF with pulmonary manifestations, lung cancer, COPD, asthma, pulmonary sarcoidosis, ILDs, emphysema, sleep apnoea, pulmonary hypertension and CRF); ^¶: CRDs significantly less at risk (p<0.05).