Table 1.
Demographic and Baseline Health Characteristics of Hospitalized Adults Testing Positive for SARS-CoV-2 by RT-PCR, by Time Period—14 Academic Medical Centers, United States, March–June and October–December 2020
| Characteristica | No. (%) | |||
|---|---|---|---|---|
| Total N = 647 | March–June N = 434 | Oct–Dec N = 213 | P-valueb | |
| Female sex | 286/645 (44) | 201/433 (46) | 85/212 (40) | 0.13 |
| Age group (years) | n = 642 | n = 429 | n = 213 | 0.086 |
| 18–49 | 157 (24) | 114 (27) | 43 (20) | |
| 50–64 | 198 (31) | 127 (30) | 71 (33) | |
| 65–74 | 147 (23) | 89 (21) | 58 (27) | |
| 75+ | 140 (22) | 99 (23) | 41 (19) | |
| Race/ethnicity | n = 632 | n = 419 | n = 213 | <0.001 |
| White, non-Hispanic | 254 (40) | 119 (28) | 135 (63) | |
| Black, non-Hispanic | 135 (21) | 103 (25) | 32 (15) | |
| Other, non-Hispanicc | 56 (9) | 50 (12) | 6 (3) | |
| Hispanic | 187 (30) | 147 (35) | 40 (19) | |
| Residence before admission | n = 628 | n = 424 | n = 204 | <0.001 |
| Community residence | 490 (78) | 299 (71) | 191 (94) | |
| Long-term care facility | 117 (19) | 105 (25) | 12 (6) | |
| Nursing home | 80 (13) | 74 (17) | 6 (3) | |
| Assisted living home | 15 (2) | 11 (3) | 4 (2) | |
| Rehab facility | 22 (4) | 20 (5) | 2 (1) | |
| Other residence | 21 (3) | 20 (5) | 1 (1) | |
| High-risk medical conditions | n = 643 | n = 434 | n = 209 | |
| Obesity (BMI ≥ 30 kg/m2) | 280/583 (48) | 159/374 (43) | 121/209 (58) | <0.001 |
| Diabetes mellitus | 243 (38) | 165 (38) | 78 (37) | 0.73 |
| Heart disease (excluding hypertension) | 146 (23) | 105 (24) | 41 (20) | 0.19 |
| Chronic kidney disease | 114 (18) | 79 (18) | 35 (16) | 0.58 |
| COPD | 65 (10) | 43 (10) | 22 (11) | 0.81 |
| Currently use tobacco | 43/604 (7) | 32/406 (8) | 11/198 (6) | 0.28 |
| Cancer | 26 (4) | 21 (5) | 5 (2) | 0.14 |
| Immunocompromised from solid organ transplant | 11 (2) | 5 (1) | 6 (3) | 0.12 |
| Currently pregnant | 14/647 (2) | 14/434 (3) | 0/213 (0) | 0.008 |
| Sickle cell disease | 5 (1) | 2 (0.5) | 3 (1) | 0.34 |
| No. of ACIP criteria met for increased risk for severe COVID-19d | n = 618 | n = 409 | n = 209 | <0.001 |
| 0 | 56 (9) | 35 (9) | 21 (10) | |
| 1 | 292 (47) | 189 (46) | 103 (49) | |
| 2 | 197 (32) | 119 (29) | 78 (37) | |
| 3 | 73 (12) | 66 (16) | 7 (3) | |
Abbreviations: ACIP, Advisory Committee on Immunization Practices; BMI, body mass index; COPD, chronic obstructive pulmonary disease; IQR, interquartile range; RT-PCR, reverse transcription-polymerase chain reaction; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.
a Among 647 hospitalized patients with SARS-CoV-2 infection, some had missing data; denominators used to calculate proportions of respondents with select characteristics excluded patients who had missing data.
b χ 2 or Fisher exact test were used for comparisons between the 2 time periods. P-values for the variables with multiple subcategories compare different distributions between 2 time periods.
c Other non-Hispanic included 7 persons who reported being American Indian/Alaska Native, 21 Asian, 4 Native Hawaiian/Other Pacific Islander, and 18 Other.
d ACIP criteria of increased risk for severe coronavirus disease 2019 (COVID-19) include: long-term care facility residents, persons aged ≥65 years, and persons aged 16–64 years with high-risk medical conditions associated with increased risk for severe COVID-19 defined by CDC (cancer; chronic kidney disease; chronic obstructive pulmonary disease; heart conditions [eg, heart failure, coronary artery disease, or cardiomyopathies]; immunocompromised state from solid organ transplant; obesity; sickle cell disease; smoking; diabetes mellitus; and pregnancy) [1].