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. 2021 May 20;21:577. doi: 10.1186/s12885-021-08332-3

Fig. 11.

Fig. 11

a Interaction network of PDE9A gene derived from GeneMANIA. GeneMANIA shows the interactions for genes linked with each other according to physical interaction, genetic interactions, co-expression, pathway, co-localization, and shared protein domain. b Protein-protein interaction network for PDE9A gene from STRING database. The interaction network shows that these 20 proteins significantly interact with PDE9A. According to the website, colored nodes represent query proteins and first shell of interactors; white nodes represent second shell of interactors; empty nodes represent proteins of unknown 3D structure; filled nodes represent some 3D structure is known or predicted