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Enrichment analysis (top 50 canonical signaling pathways) of the predicted target genes by up (left) and down (right) regulated plasmatic miRNAs. Enrichment analysis performed by Ingenuity Pathway Analysis (IPA®, Qiagen bioinformatics). The dashed line represents –log (p-value) = 1.3 or p-value = 0.05 (Fisher’s exact test). The ratios between the target miRNA genes and all genes involved in the specific signaling pathway are represented on the right side of each bar
