Table 2.
Type of parameter | Parameter | Probabilitya | Source | Lowb | Highb | |
---|---|---|---|---|---|---|
Location of first encounter | Inpatient | .20 | [13] | .10 | .30 | |
Outpatient | .80 | .90 | .70 | |||
Volume of ascites | Inpatient | Mild | .20 | [15] | .30 | .10 |
Moderate | .60 | .60 | .60 | |||
Large | .20 | .10 | .30 | |||
Outpatient | Mild | .40 | .50 | .30 | ||
Moderate | .50 | .50 | .50 | |||
Large | .10 | .00 | .20 | |||
Response to therapy | Mild | Ascites resolves | .92 | [5–9] | 1.00 | .82 |
Partially improves | .07 | .00 | .07 | |||
No response | .01 | .00 | .11 | |||
Moderate | Ascites resolves | .65 | .75 | .55 | ||
Partially improves | .30 | .35 | .30 | |||
No response | .05 | .00 | .15 | |||
Large | Ascites resolves | .35 | .45 | .25 | ||
Partially improves | .50 | .50 | .50 | |||
No response | .15 | .05 | .25 | |||
Type of treatment complication | Ascites resolves | No complication | .82 | [5–9] | .92 | .72 |
Minor complication | .14 | .08 | .14 | |||
Major complication | .04 | .00 | .14 | |||
Partially improves | No complication | .50 | .60 | .40 | ||
Minor complication | .25 | .25 | .25 | |||
Major complication | .25 | .15 | .35 | |||
No response | No complication | .20 | .30 | .10 | ||
Minor complication | .35 | .35 | .35 | |||
Major complication | .45 | .35 | .55 | |||
Subsequent care encounters | No complication | 0, 1, 2 visits | .10, .70, .20 | [5–9] | .20, .70, .10 | .00, .70, .30 |
0, 2, 6 LVPs | .70, .20, .10 | .80, .20, .00 | .60, .20, .20 | |||
0, 1, 2 admits | .90, .08, .02 | 1.00, .00, .00 | .80, .08, .12 | |||
Minor complication | 0, 1, 2 visits | .05, .45, .50 | .15, .45, .40 | .00, .40, .60 | ||
0, 2, 6 LVPs | .50, .35, .15 | .60, .35, .05 | .40, .35, .25 | |||
0, 1, 2 admits | .83, .13, .04 | .93, .07, .00 | .73, .13, .14 | |||
Major complication | 0, 1, 2 visits | .05, .37, .58 | .15, .37, .48 | .00, .32, .68 | ||
0, 2, 6 LVPs | .20, .45, .35 | .30, .45, .25 | .10, .45, .45 | |||
0, 1, 2 admits | 0, .58, .42 | .10, .58, .32 | 0, .48, .52 |
aProbability of each patient experiencing this event within a 6-month window of the first encounter
b “Low” sensitivity analysis is 10% lower than the predicted probability. “High” sensitivity analysis is 10% higher than the predicted probability
c3 probabilities on each row