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. 2021 May 6;12:681110. doi: 10.3389/fimmu.2021.681110

Figure 1.

Figure 1

An overview of BM-dependent ILC and thymus-dependent T-cell development. Current models for both ILC and T-cell development suggest that they are of distinct lineages and that the site for maturation do not overlap beyond the CLP stage. ILCs have been proposed to develop in the BM whereas committed T-cell progenitors undergo intense development processes that are heavily influenced by the thymic niche.