How this fits in

Urinary tract infections (UTIs) are often treated with antibiotics and are a major source of antibiotic overuse. In the interests of decreasing antibiotic prescribing, one alternative treatment is methenamine hippurate, which has reported benefits and a mild side-effect profile; however, its comparative effectiveness has not been widely explored. This study focused on the efficacy of methenamine hippurate compared with both control/no treatment and any antibiotic. Overall, the insufficiency of evidence precludes a firm recommendation on the use of methenamine hippurate prophylactically; however, there is enough evidence to warrant further research to investigate its benefits.