Table 4. Design of Central Composite Design (CCD) and its actual values.

Run	A	B	C	Yield (%)		Crystal size (nm)		Crystallinity (%)
	Temp* (°C)	Time (h)	pH	Actual	Predict	Actual	Predict	Actual	Predict
1	100	4	4	46.18	43.33	60.23	59.59	55.83	55.88
2	160	10	10	89.75	92.79	45.48	47.00	86.13	86.82
3	70	7	7	65.44	72.03	28.76	28.00	68.86	68.88
4	130	7	13	84.61	84.88	46.81	45.14	72.92	72.18
5	160	4	4	48.70	46.83	84.10	85.12	58.07	58.48
6	130	7	1	0	-	-	-	-
7	100	10	4	47.5	50.04	65.15	64.95	57.50	57.43
8	160	4	10	83.80	86.08	38.98	41.63	82.53	83.34
9	130	7	7	74.74	75.53	45.82	47.52	76.85	77.88
10	130	7	7	75.85	75.53	46.88	47.52	77.89	77.88
11	130	1	7	68.25	68.82	44.10	44.16	75.16	74.70
12	160	10	4	51.64	53.54	89.00	90.48	59.14	59.49
13	100	10	10	91.00	89.29	31.59	33.48	78.88	79.21
14	130	13	7	88	82.25	56.18	52.88	80.01	79.72
15	100	4	10	87	82.58	29.18	28.12	74.82	75.21
16	190	7	7	78.34	79.04	71.15	67.04	79.84	79.08
17	130	7	7	77.3	75.53	44.77	47.52	74.82	75.21

*Temperature