Table 3. Subgroup analysis for comparison of genotype distribution in Southeast Asia based on the period of data collection.

Period of data collection	Number of studies	Prevalence (%)	95% CI	I2 (%)	Q	Heterogeneity test
						DF	p
Genotype 1
< 2000	22	60.1	49.8–69.6	91.50	246.973	21	< 0.001
2000–2009	24	40.7	33.2–48.6	93.05	330.765	23	< 0.001
2010–2020	44	44.5	40.1–49.0	92.95	609.605	43	< 0.001
Overall	90	46.8	43.2–50.4	92.77	1230.186	89	< 0.001
Genotype 2
< 2000	22	12.1	8.3–17.2	78.06	95.724	21	< 0.001
2000–2009	24	4.2	2.4–7.0	82.94	134.849	23	< 0.001
2010–2020	44	2.5	1.7–3.8	90.99	477.014	43	< 0.001
Overall	90	4.6	3.5–5.9	88.84	797.228	89	< 0.001
Genotype 3
< 2000	22	15.5	9.8–23.6	89.10	192.586	21	< 0.001
2000–2009	24	21.2	13.8–31.1	94.52	419.506	23	< 0.001
2010–2020	44	27.0	21.9–32.9	93.38	649.669	43	< 0.001
Overall	90	23.1	19.4–27.2	93.03	1277.648	89	< 0.001
Genotype 4
< 2000	22	1.2	0.7–2.0	0	9.890	21	0.980
2000–2009	24	1.0	0.4–2.4	67.89	71.628	23	< 0.001
2010–2020	44	1.0	0.6–1.6	52.78	91.073	43	< 0.00
Overall	90	1.1	0.7–1.5	49.88	177.585	89	< 0.00
Genotype 5
< 2000	22	1.3	0.4–4.7	87.06	162.244	21	< 0.001
2000–2009	24	0.7	0.4–1.2	0	14.872	23	0.899
2010–2020	44	0.6	0.4–0.9	0	43.161	43	0.464
Overall	90	0.8	0.4–1.3	79.25	428.906	89	< 0.001
Genotype 6
< 2000	22	4.0	2.2–7.2	80.86	109.699	21	< 0.001
2000–2009	24	20.5	13.9–29.2	94.48	416.986	23	< 0.001
2010–2020	44	19.6	15.8–24.1	94.95	852.257	43	< 0.001
Overall	90	16.5	13.8–19.6	93.98	1479.449	89	< 0.001