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. 2021 May 20;16(5):e0251911. doi: 10.1371/journal.pone.0251911

Fig 2. Loss of spermatogenesis in the seminiferous tubules of ΔCtnnb1 mice.

Fig 2

A) Time course analysis of testicular weight comparing ΔCtnnb1 to control mice at the indicated ages. Sample numbers analyzed varied by age and genotype. Values for ΔCtnnb1 are 1M: n = 4; 2M: n = 6; 4M: n = 14; 8M: n = 8; 10M: n = 14; values for control are 1M: n = 4; 2M: n = 8; 4M: n = 18; 8M: n = 8; 10M: n = 12. Data are expressed as means (columns) ± SEM (error bars). Asterisks indicate significant differences from controls (** P < 0.01; **** P < 0.0001). B) Photomicrographs comparing testicular histology of ΔCtnnb1 to control mice at the indicated ages. Scale bar (lower right) is valid for all images; Hematoxylin and Eosin staining.