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. 2021 May 20;16(5):e0251966. doi: 10.1371/journal.pone.0251966

Table 1. Demographic, clinical characteristics and laboratory findings and outcomes of the entire cohort of patients.

Total number of patients = 227
Age years (mean±SD) 72±13
Age> 70 years, n (%) 127 (57)
Male gender, n (%) 129 (56.8)
Clinical features
Hypertension, n (%) 129 (56.8)
Cardiovascular disease, n (%) 77 (33.9)
Diabetes, n (%) 55 (24.2)
COPD, n (%) 37 (16.2)
Obesity (BMI>30 Kg/m2), n (%) 25 (11)
Cancer, n (%) 20 (8.8)
Main laboratory findings
Platelet count, 109/L (mean±SD) 220567±96698
White Blood Cell, 109/L (mean±SD) 8.78±11.87
Creatinine, mg/dL (mean±SD) 1.33±1.29
PT, activity % (mean±SD) 72.3±15.5
aPTT, seconds (mean±SD) 36.6±45.1
Fibrinogen, mg/dL (mean±SD) 599±166
C reactive protein, mg/L, (median—IQR) 16.5 (6.7–56.5)
D-dimer value on admission, ng/mL (median–IQR) 1483 (576–7732)
D-dimer peak value, ng/mL (median—IQR) 1865 (1046–5682)
D-dimer peak value 1st quartile, ng/mL < 1046
D-dimer peak value 2nd quartile, ng/mL 1046–1865
D-dimer peak value 3rd quartile, ng/mL 1866–5682
D-dimer peak value 4th quartile, ng/mL >5682
Padua Prediction Score
5, n (%) 79 (34.8)
6, n (%) 119 (52.4)
>6, n (%) 29 (12.8)
Mean±SD 5.91±1.0
Diagnosis of DVT
Total, n (%) 31 (13.7)
Proximal, n (%) 14 (6.2)
Distal, n (%) 17 (7.5)
Timing of DVT diagnosis since admission
Day 0–3, n (%) 18 (58.1)
Day 5–8, n (%) 11 (35.5)
Day 12–15, n (%) 2 (6.4)
Outcome measures
In-hospital length of stay, days (mean±SD) 12.2±6.7
Step up to ICU, n (%) 12 (5.3)
In-hospital death, n (%) 22 (9.7)
Step up to ICU or in-hospital death, n (%) 34 (15)

COPD: Chronic obstructive pulmonary disease; PT: prothrombin time; aPTT: activated partial thromboplastin time; DVT: deep vein thrombosis; ICU: Intensive Care Unit.