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. 2021 Apr 22;49(9):5017–5027. doi: 10.1093/nar/gkab275

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© The Author(s) 2021. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 8. — The contact probability of a promoter to the surface of the transcriptional condensate is shown as a function of the ratio of time scales for cases in which the loop extrusion is active (magenta) and not active (cyan). We used α_elo = 0.3 and ρ/K_elo = 2.2 for the calculations. For the magenta line we set , 2k_BTτ_m/(ζ₀a²) = 5.0 (the cyan line corresponds to ). The ratio scales linear to the number N₀ of units in the linker chromatin, whereas the time scale does not depend on the number N₀ of units.

Inline graphic — The contact probability of a promoter to the surface of the transcriptional condensate is shown as a function of the ratio of time scales for cases in which the loop extrusion is active (magenta) and not active (cyan). We used α_elo = 0.3 and ρ/K_elo = 2.2 for the calculations. For the magenta line we set , 2k_BTτ_m/(ζ₀a²) = 5.0 (the cyan line corresponds to ). The ratio scales linear to the number N₀ of units in the linker chromatin, whereas the time scale does not depend on the number N₀ of units.