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. 2021 May 1;49(9):5393–5406. doi: 10.1093/nar/gkab253

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© The Author(s) 2021. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Models for ICF and DNF circuits based on biochemical reactions. (A) Schematic diagram for molecular ICF network. Molecule Z is activated by molecule X and repressed by molecule Y, which is activated by X. (B) Simulation results of FCA and MDL for molecular ICF circuit. (C) Schematic diagram for molecular DNF circuit. Similar to the ICF, but here the molecule Z also represses Y. (D) Simulation results of FCA and MDL for the molecular DNF circuit. Simulation parameters: β = 0.1, α = 10, n = 1.5, m = 1, h = 1.