Figure 2.

Extension traces from single molecules containing cKIT-2, hTelo 21-TTA, cMYC-Pu27 or ori β^A G4 forming sequences. (A) From top to bottom, cKIT-2, hTelo 21-TTA, cMYC and ori β^A G4 forming sequences in 100 mM KCl and blocking oligonucleotide. (B) ori β^A G4 forming sequence in KCl without blocking oligonucleotide (top) and in LiCl plus blocking oligonucleotide (middle). cMYC-Pu27 in LiCl plus oligonucleotide (bottom). Formation of a G4 structure is detected by a blockage at 7 pN (red), as described in Figure 1. Single G4 events are underlined (red).