Table 1. Expression levels of GABA(A)R subunits in various types of immune cells.
Subunit/Cell type | Mouse CD4+ | Mouse CD8+ | Human T cells | Human B-cells | Human monocytes | Human NK cells |
---|---|---|---|---|---|---|
α1 | - | - | ++ | ++ | + | - |
α2 | ++ | + | - | - | - | - |
α3 | ++ | ++ | - | - | - | - |
α4 | - | - | + | + | + | + |
α5 | +++ | +++ | ++ | - | - | - |
α6 | - | - | - | - | - | - |
β1 | - | - | ++ | ++ | ++ | - |
β2 | +++ | ++ | + | ++ | - | - |
β3 | +++ | + | + | - | - | - |
γ1 | ++ | ++ | - | - | - | - |
γ2 | + | + | - | - | - | - |
γ3 | - | - | - | - | - | - |
δ | +++ | +++ | ++ | - | + | - |
ε | - | - | - | - | - | - |
π | - | - | ++ | ++ | ++ | ++ |
θ | - | - | - | - | - | - |
ρ1 | - | - | ++ | - | + | ++ |
ρ2 | - | - | +++ | ++ | ++ | ++ |
ρ3 | - | - | - | - | - | - |
The expression levels indicated are based on the thickness and intensity of the bands in the gel. “+++” represents high level of expression, “++”—medium, “+”—weak expression and “- “–expression not detected.