Table 1.
Experimental design and different treatments
| Breed | Experiment Groups | Challenge with Cl. Perfringens | Treatments a , b | |||||
|---|---|---|---|---|---|---|---|---|
| Name | Code | Time | Dose | Route | Type | Time | Route | |
| Cobb | Control negative | IA | — | — | — | — | — | — |
| Control positive | IB | day 16 to 18 post‐hatch | 1 × 109 cfu /bird | crop gavage | — | — | — | |
| Antibiotic treatment a | IC | Flagymox® | once daily /17−19 day Post‐hatch | D.W. | ||||
| Microbial based treatment b | ID | Big‐lactoα® | ||||||
| Arbor Acres | Control negative | IIA | — | — | — | — | — | — |
| Control positive | IIB | day 16 to 18 post‐hatch | 1 × 109 cfu /bird | crop gavage | — | — | — | |
| Antibiotic treatment a | IIC | Flagymox® | once daily /17−19 day Post‐hatch | D.W. | ||||
| Microbial based treatment b | IID | Big‐lactoα® | ||||||
a
Flagymox®: it is manufactured by ATCO Pharma Trading Co., Egypt and each 100 mg of product contain 10 mg amoxicillin plus 20 mg metronidazole.
b
Big‐lactoα ®: it is provided by Biogenoci Co ltd. Its ingredients are Lactobacillus acidophilus (5x108CFU/ vial) and bacteriophage (>1x108 PFU/g).