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. 2021 May 21;100(20):e24571. doi: 10.1097/MD.0000000000024571

Table 2.

Adverse effects in the included studies according to the formulation of intravenous iron.

Studies (first author, date of publication) Iron formulation administered Adverse events (number of patients)
Lee 2018 FCM and IS Headache (4, no details for the included group)
Jose 2019 FCM Injection site reaction (1), elevated serum transaminase level (1), hypophosphatemia (2)
IS Injection site reaction (2), epigastric pain (2), hypophosphatemia (3)
Naqash 2018 FCM Headache (1)
IS Nausea and tingling sensation (3), headache (2), arthralgia (1)
Sumathy 2017 FCM Nausea, giddiness, arthralgia (total 3)
IS Nausea, vomiting, urticaria (total 7)
Mahey 2016 FCM Gastritis (2), itching (2), rash (1), hypophosphatemia (15)
IS Fever (2), gastritis (2), vomiting (2), injection site pain (3), itching (1), hypophosphatemia (12)
Joshi 2016 FCM Chest discomfort (2), nausea (1)
IS Injection site reaction, nausea, hypotension (total 6)
Garg 2015 FCM Injection site reaction (1), rash (1), headache (3), nausea (1)
IS Injection site reaction (2), rash (2), headache (4), nausea (2)
Hol 2015 FCM Rigors (1), headache (2), flushing or skin eruption (1), itching (2), injection site pain or redness (3)
IS Rigors (1), headache (1), itching (3), injection site pain or redness (5), nausea and vomiting (2)
Rathod 2015 FCM Arthralgia or tingling sensation (1)
IS Transient hypotension (3), arthralgia or tingling sensation (3)