Table 3.
Sensitivity of different urinary biomarkers to predict BC by histological grade.
| Biomarker n° of studies (n° of pts) | Cytology n = 14 (7585) | UroVysion n = 6 (1997) | BTA stat n = 4 (584) | ImmunoCyt n = 5 (3350) | NMP-22 n = 11 (4867) |
|---|---|---|---|---|---|
| G1 | |||||
| Mean ± SD | 24.4 ± 22.2 | 66.5 ± 34.2 | 42.9 ± 5.7 | 67.3 ± 15.5 | 48.0 ± 25.7 |
| Median | 16.0 | 61.5 | 42.9 | 69.2 | 48.2 |
| Range | 0–67.7 | 20.0–100.0 | 36–50.0 | 47.0–85.7 | 5.1–100.0 |
| G2 | |||||
| Mean ± SD | 41.9 ± 25.5 | 75.2 ± 23.1 | 61.9 ± 17.4 | 69.7 ± 13.3 | 54.8 ± 26.5 |
| Median | 36.1 | 63.0 | 69.1 | 75.0 | 53.3 |
| Range | 16.0–87.0 | 51.4–100.0 | 36.0–73.3 | 47–79.9 | 5.1–100.0 |
| G3 | |||||
| Mean ± SD | 69.6 ± 19.2 | 95.5 ± 7.3 | 89.7 ± 2.0 | 85.2 ± 5.0 | 76.9 ± 16.2 |
| Median | 74.0 | 100.0 | 89.7 | 83.3 | 76.9 |
| Range | 37.5–100.0 | 83.3–100.0 | 87.5–91.7 | 79.0–91.3 | 36.4–100.0 |
pts = patients; SD = standard deviation.