Table 2.

Optimal cutoff values of bronchoalveolar lavage fluid, serum interleukin-27, and sputum smear for the diagnostic value calculated using ROC curves, using the final diagnosis as the gold standard.

	AUC (95% CI)	P value	Cutoff	Sensitivity (%)	Specificity (%)	Accuracy (%)	+LR	–LR	PPV (%)	NPV (%)
All populations (n = 127)
Sputum smear	0.614 (0.523–0.699)	<.001	N/A	22.7	100	46.4	—	0.77	100	36.4
Serum IL-27	0.703 (0.616–0.781)	<.001	65.55	45.5	89.7	59.1	4.43	0.61	90.9	42.2
BALF IL-27	0.897 (0.830–0.944)	<.001	86.26	92	71.8	85.8	3.26	0.11	88	80
Population with a negative sputum smear result (n = 68)
Serum IL-27	0.679 (0.601–0.782)	<.001	65.55	47.1	89.7	62.6	4.59	0.59	88.9	49.3
BALF IL-27	0.882 (0.805–0.936)	<.001	86.26	91.2	71.8	84.1	3.23	0.12	84.9	82.4