Table 3.
Overall survival | Recurrence-free survival | |||||||
Factors | Univariate analysis | Multivariate analysis | Univariate analysis | Multivariate analysis | ||||
P | HR (95%CI) | P | HR (95%CI) | P | HR (95%CI) | P | HR (95%CI) | |
Gender (male/female) | .049 | 0.586 (0.345–0.997) | .400 | .662 | ||||
Age (>60 vs ≤60, Month) | .058 | .109 | ||||||
Total Bilirubin, umol/L | .718 | .338 | ||||||
ALT, IU/L | .940 | .159 | ||||||
Albumin, g/L | .764 | .771 | ||||||
ΔNLR (>0 vs ≤0) | .006 | 0.622 (0.445–0.871) | .024 | 0.678 (0.483–0.950) | .022 | 0.700 (0.515–0.951) | .050 | 0.736 (0.541–1.000) |
Differentiation (Low, Moderate, High) | .001 | 0.420 (0.254–0.694) | .103 | .007 | 0.523 (0.325–0.840) | .002 | 0.467 (0.287–0.761) | |
MVI (Yes vs No) | <.001 | 3.730 (2.242–6.208) | <.001 | 5.445 (2.842–10.012) | .004 | 2.218 (1.295–3.799) | .018 | 2.043 (1.130–3.692) |
Tumor Size (<5 vs ≥5, cm) | .237 | .455 | ||||||
Cirrhosis (Yes vs No) | .059 | .769 | ||||||
AFP (≤400 vs >400, ng/mL) | <.001 | 2.448 (1.498–4.001) | .012 | 2.036 (1.168–3.548) | <.001 | 2.637 (1.649–4.217) | <.001 | 2.610 (1.575–4.326) |
HBeAg (Positive vs Negative)) | .389 | .407 | ||||||
HBV-DNA (≥2 × 103 vs 2 × <103, IU/mL) | .136 | .007 | 0.506 (0.307–0.834) | .208 | ||||
Antiviral Therapy (NtA vs NsA) | .043 | 0.722 (0.217–0.996) | .045 | 0.859 (0.531–0.907) | .028 | 0.373 (0.307–0.698) | .041 | 0.768 (0.536–0.979) |
Transfusion (Yes vs No) | .394 | .665 | ||||||
Complication (Yes vs No) | .343 | .136 | ||||||
Immunotherapy (none Tα1 vs Tα1) | .018 | 0.542 (0.324–0.908) | <.001 | 0.308 (0.175–0.541) | .006 | 0.517 (0.317–0.842) | <.001 | 0.381 (0.229–0.633) |