Table 2.

Descriptive statistics: CIE-L*-, a*, and b* values of infiltrated white spot lesion and sound adjacent enamel as well as WSL/SAE differences at the distinct time points. Data are dependent, ie, each value has been compared to its baseline value^a

Time Points Compared:		Area	Parameter	Mean ± SD		Diff.	P	CI 95%
Time 1	Time 2			Time 1	Time 2
T0	T6	WSL	L	73.9 ± 4.84	70.96 ± 3.36	2.94	<.001	[1.57; 4.3]
T0	T12	WSL	L	74.1 ± 3.83	71.01 ± 3.87	3.09	.02	[0.52; 5.66]
T0	T24	WSL	L	73.94 ± 4.64	71.4 ± 3.44	2.5	<.001	[1.22; 3.79]
T0	T6	SAE	L	73.62 ± 2.4	73.4 ± 1.84	0.2	.5	[−0.35; 0.75]
T0	T12	SAE	L	73.57 ± 2.83	73.33 ± 1.97	0.24	.63	[−0.82; 1.29]
T0	T24	SAE	L	73.5 ± 2.32	73.4 ± 1.8	0.1	.64	[−0.33; 0.52]
T0	T6	WSL-SAE	Diff L	0.2 ± 4.57	−2.5 ± 3.25	2.7	<.001	[1.47; 3.94]
T0	T12	WSL-SAE	Diff L	0.53 ± 3.03	−2.3 ± 3.17	2.85	.006	[0.93; 4.77]
T0	T24	WSL-SAE	Diff L	0.44 ± 4.36	−1.96 ± 3.32	2.4	<.001	[1.25; 3.56]
T0	T6	WSL	a	6.1 ± 2.84	6.63 ± 2.49	−0.53	.2	[−1.35; 0.28]
T0	T12	WSL	a	6.14 ± 1.93	7.42 ± 1.67	−1.28	.009	[−2.19; −0.37]
T0	T24	WSL	a	6.09 ± 2.62	6.85 ± 2.44	−0.76	.04	[−1.49; −0.03]
T0	T6	SAE	a	5.13 ± 1.26	4.83 ± 1.39	0.3	.049	[0; 0.4]
T0	T12	SAE	a	5.16 ± 1.28	4.6 ± 1.17	0.56	.03	[0.08; 1.04]
T0	T24	SAE	a	5.00 ± 1.37	5.22 ± 1.2	0.22	.09	[−0.03; 0.47]
T0	T6	WSL-SAE	Diff a	1.03 ± 2.93	1.88 ± 2.58	−0.85	.04	[−1.65; −0.04]
T0	T12	WSL-SAE	Diff a	0.97 ± 1.65	2.8 ± 1.741	−1.84	<.001	[−2.45; −1.22]
T0	T24	WSL-SAE	Diff a	0.87 ± 2.54	1.85 ± 2.76	−0.98	.007	[−1.68; −0.28]
T0	T6	WSL	b	15.69 ± 8.66	20.9 ± 3.92	−5.21	<.001	[−7.69; −2.72]
T0	T12	WSL	b	13.19 ± 4.22	22.27 ± 2.77	−9.08	<.001	[−11.38; −6.79]
T0	T24	WSL	b	15.79 ± 7.94	20.92 ± 3.84	−5.13	<.001	[−7.21; −3.05]
T0	T6	SAE	b	20.66 ± 3.25	22.15 ± 2.78	−1.49	<.001	[−2.18; −0.8]
T0	T12	SAE	b	20.64 ± 3.47	22.99 ± 2.38	−2.35	<.001	[−3.68; −1.03]
T0	T24	SAE	b	20.85 ± 3.18	22.18 ± 2.78	−1.33	<.001	[−1.8; −0.86]
T0	T6	WSL-SAE	Diff b	−4.8 ± 7.94	−1.16 ± 3.17	−3.63	.003	[−5.91; −1.36]
T0	T12	WSL-SAE	Diff b	−7.45 ± 4.52	−0.72 ± 2.8	−6.73	<.001	[−8.48; −4.98]
T0	T24	WSL-SAE	Diff b	−5.06 ± 7.3	−1.25 ± 3.48	−3.8	<.001	[−5.76; −1.84]

^aWSL indicates white spot lesion; SAE, sound adjacent enamel.