Table 1.

Risk–benefit of rotavirus vaccination by country on rotavirus hospitalisations and deaths and associated intussusception risk for one vaccinated birth cohort to age 5 years

Country	Vaccine evaluated	Vaccine dose(s)	Overall attributable risk*	Rotavirus outcomes averted	Intussusception outcomes caused
Mexico34	Rotarix	Dose 1 only	2.0–3.7	Hospitalisations: 11 551 Deaths: 663	Hospitalisations: 41 Deaths: 2
Brazil34	Rotarix	Dose 2 only	1.5	Hospitalisations: 69 572 Deaths: 640	Hospitalisations: 55 Deaths: 3
Australia35	Rotarix	Doses 1 and 2	4.3	Hospitalisations: 6528 Deaths: not reported	Hospitalisations: 14 Deaths: not reported
	RotaTeq	Doses 1 and 2	7.0
USA36 39	Rotarix	Doses 1 and 2	5.3	Hospitalisations: 53 444 Deaths: 14	Hospitalisations: 35–166 Deaths: 0.1–0.5
		Dose 2 only	7.3
	RotaTeq	Dose 1 only	0.7–1.5	Not reported	Not reported
England40	Rotarix	Dose 1 only	1.68	Hospitalisations: 25 000 Deaths: not reported	Hospitalisations: 21 Deaths: not reported

Note: Table adapted from Reference.⁸⁷

*Excess intussusception cases per 100 000 vaccinated infants.