Table 2.
Anti-pituitary antibodies by IIF on human pituitary substrate
| Control N=40 |
IAD N=17 |
Hypophysitis N=5 |
|
| Pre APA (+) | 1 | 11* | 0 |
| Type of cell | |||
| ACTH | 1/1 | 11/11 | |
| TSH | 0/1 | 4/11 | |
| FSH | 1/1 | 11/11 | |
| LH | 0/1 | 1/11 | |
| GH | 0/1 | 0/11 | |
| PRL | 0/1 | 0/11 | |
| Post APA (+) | – | 15 | 4 |
| Type of cell | |||
| ACTH | 15/15 | 4/4 | |
| TSH | 13/15 | 4/4 | |
| FSH | 15/15 | 4/4 | |
| LH | 12/15 | 3/4 | |
| GH | 7/15 | 3/4 | |
| PRL | 1/15 | 2/4 |
*P<0.05 compared with the control.
ACTH, adrenocorticotropic hormone; Post APA, anti-pituitary antibodies at onset; Pre APA, anti-pituitary antibodies at baseline; FSH, follicle stimulating hormone; GH, growth hormone; IAD, isolated ACTH deficiency; IIF, indirect immunofluorescence; LH, luteinizing hormone; PRL, prolactin; TSH, thyroid stimulating hormone.