Table 2.
Pregnancy outcomes in women with AS and controls: Korean HIRA claims database
| Outcome | With AS (n = 1,293) | Without AS (n = 12,926) | OR | 95% CI | Adjusted OR | 95% CI |
|---|---|---|---|---|---|---|
| No complication (ref) | 602 (46.6) | 7,421 (57.4) | 1.00 | 1.00 | ||
| Overall complication | 691 (53.4) | 5,505 (42.5) | 1.55 | 1.38–1.73 | 1.52a | 1.36–1.70 |
| Caesarean section | 657 (50.8) | 5,098 (39.3) | 1.58 | 1.41–1.77 | 1.56a | 1.39–1.74 |
| Preeclampsia | 17 (1.3) | 101 (0.8) | 1.70 | 1.01–2.86 | 1.56b | 0.91–2.67 |
| Preterm delivery | 18 (1.4) | 174 (1.3) | 1.06 | 0.65–1.71 | 1.05c | 0.54–1.68 |
| Placental abruption | 0 (0.0) | 23 (0.2) | NE | |||
| Other obstetric trauma | 16 (1.2) | 239 (1.8) | 0.66 | 0.40–1.10 | 0.64d | 0.39–1.07 |
| Maternal distress during labour and delivery | 0 | 10 (0.2) | NE | |||
| Twin pregnancy | 10 (0.8) | 82 (0.6) | 1.21 | 0.63–2.34 | 1.41d | 0.75–2.07 |
Values are presented as number (%).
AS, ankylosing spondylitis; HIRA, Health Insurance Review and Assessment Service; OR, odds ratio; CI, confidence interval; NE, not estimated.
a
Adjusted for parity, twin pregnancy, presence of hypertension and diabetes mellitus.
b
Adjusted for presence of hypertension.
c
Adjusted for twin pregnancy, presence of hypertension and diabetes mellitus.
d
Adjusted for parity. Odds ratio of maternal complications compared between two groups using a generalized linear model with binomial distribution to account for the matched nature of the data.