Table 2.
Clinical characteristics of patients with BrS in international registries
| Characteristic | Korean IA Registry [18] (n = 90) | Japanese multi-center registry [43] (n = 415) | Sieira et al. [44] (Belgium) (n = 404) | Delise et al. [45] (Italy) (n = 320) | FINGER registry [46] (n = 1,029) | Eckardt et al. [47] (Europe) (n = 212) | Brugada et al. [48] (Europe) (n = 443) | Priori et al. [38] (Italy) (n = 200) | Brugada et al. [49] (n = 334) |
|---|---|---|---|---|---|---|---|---|---|
| Mean age, yr | 41 ± 13 | 46 ± 14 | 43 ± 16 | 43 | 45 | 45 ± 6 | 42 ± 14 | 41 ± 18 | 42 ± 16 |
| Male sex | 84 (93) | 403 (97) | 235 (58.2) | 258 (81) | 745 (72) | 152 (72) | 342 (77) | 152 (76) | 225 (67) |
| History of syncope | 27 (30) | 99 (24) | 114 (28) | 105 (34) | 313 (30) | 65 (31) | 100 (23) | 34 (17) | 73 (22) |
| History of SCD | 50 (56) | 88 (21) | 17 (4.2) | NA | 62 (6) | 24 (11) | 80 (18) | 22 (11) | 71 (21) |
| Family history of SCD | 23 (26) | 64 (15) | 187 (47) | 94 (29) | 264 (26) | 60 (28) | NA | 26/130 (22) | 180 (54) |
| ICD implantation | 70 (78) | 241 (58) | 168 (42) | 110 (34) | 433 (42) | 113 (53) | NA | 52 (26) | 129 (39) |
| Type I ECG | 50/56 (89) | 299 (72) | NA | 174 (54) | 468 (45) | 125 (59) | NA | 90/176 (51) | NA |
| SCN5A genotype | NA | 60 (14) | 53 (22) | NA | 185 (18) | 57/183 (31) | NA | 28/130 (22) | NA |
Values are presented as mean ± SD or number (%).
BrS, Brugada syndrome; IA, inherited arrhythmia; FINGER, France, Italy, Netherlands, GERmany; SCD, sudden cardiac death; NA, not available; ICD, implantable cardioverter defibrillator; ECG, electrocardiogram; SCN5A, sodium voltage-gated channel alpha subunit 5.