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. 2021 Feb 2;8(5):ofab046. doi: 10.1093/ofid/ofab046

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© The Author(s) 2021. Published by Oxford University Press on behalf of Infectious Diseases Society of America.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 1. — Fraction of participants with respective number of genomic positions with at least 1 major resistance-associated mutation (RAM) (with a variant frequency >5%) at respective time point¹. ¹ Observed major RAMs: M41L, A62V, K65R, D67N, K70E, K70R, V75I, F77L, Y115F, M184V, M184I, L210W, T215Y, T215F, K219Q, K219E, L100I, K101P, K101E, K103N, K103S, V106M, V108I, E138A, E138G, E138Q, Y181C, Y188C, Y188L, Y188H, V179L, G190A, G190S, H221Y, P225H, M230L, M230I, D30N. EAC, enhanced adherence counseling; NNRTI, nonnucleoside reverse-transcriptase inhibitor; NRTI, nucleoside reverse-transcriptase inhibitor.