Table 3.

Hemodynamic parameters at baseline, after 4 weeks, and after 8 weeks of supplementation

	Placebo			OLE			Uncorrected p1	Uncorrected p2
	Baseline	4 weeks	8 weeks	Baseline	4 weeks	8 weeks
Systolic BP (mmHg)	131 ± 2	129 ± 2	131 ± 2	128 ± 2	128 ± 2	127 ± 2	0.501	0.731
Diastolic BP (mmHg)	82 ± 2	81 ± 2	82 ± 1	80 ± 2	80 ± 2	79 ± 1	0.029a	0.590
MAP (mmHg)	99 ± 2	97 ± 2	98 ± 2	96 ± 2	96 ± 2	95 ± 2	0.095	0.905
Pulse pressure (mmHg)	49 ± 1	49 ± 2	49 ± 1	49 ± 1	48 ± 1	48 ± 1	0.473	0.428
HR (bpm)	66 ± 2	67 ± 2	68 ± 2	67 ± 2	67 ± 2	67 ± 2	0.803	0.532

All values are presented as mean ± SEM. Differences between the placebo and OLE were compared with an unstructured linear mixed model with correction for baseline values. p₁ and p₂ represent the p values for the difference in estimated means after 4 and 8 weeks of intervention, respectively, between placebo and OLE, corrected for baseline differences

BP blood pressure, MAP mean arterial pressure, HR heart rate, OLE olive leaf extract

^ap > 0.05 after correction for multiple testing by the false-discovery rate (FDR) of Benjamini–Hochberg (10 tests)