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NK cell specific signaling domains incorporated within CAR intracellular domains
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Abbreviations: DAP12, DNAX Activating Protein of 12KDa; DAP10, DNAX Activating Protein of 12KDa; ITAM, immunoreceptor tyrosine-based activation motif; ITSM, immunoreceptor tyrosine-based switch motif; YXXM, Y stands for tyrosine, X for any amino acid residue, and M for methionine; TRAF1–3, tumor necrosis factor receptor-associated factors 1, 2 and 3.
